Xenon Xe 133 Gas
Name: Xenon Xe 133 Gas
External radiation
The specific gamma ray constant for Xenon Xe 133 is 0.51 R/hr-mCi at 1 cm. The first half-value thickness is 0.0035 cm of Pb.
A range of values for the relative attenuation of the radiation emitted by this radionuclide that results from interposition of various thicknesses of Pb is shown in Table 3. For example, the use of 0.2 cm of Pb will decrease the external radiation exposure by a factor of about 1000.
Table 3. Radiation Attenuation by Lead Shielding
| Shield Thickness (Pb), cm | Coefficient of Attenuation |
| 0.0035 | 0.5 |
| 0.037 | 10-1 |
| 0.12 | 10-2 |
| 0.20 | 10-3 |
| 0.29 | 10-4 |
To correct for physical decay of this radionuclide, the fractions that remain at selected time intervals after the date of calibration are shown in Table 4.
Table 4. Physical Decay Chart; Xenon Xe 133, Half-life 5.245 Days
| * Calibration Date | |||
| Days | Fraction Remaining | Days | Fraction Remaining |
| 0* | 1.000 | 8 | 0.347 |
| 1 | 0.876 | 9 | 0.304 |
| 2 | 0.768 | 10 | 0.267 |
| 3 | 0.673 | 11 | 0.234 |
| 4 | 0.589 | 12 | 0.205 |
| 5 | 0.516 | 13 | 0.179 |
| 6 | 0.453 | 14 | 0.157 |
| 7 | 0.397 | ||
Contraindications
None known.
Warnings
Xenon Xe 133 Gas delivery systems, i.e., respirators or spirometers, and associated tubing assemblies must be leakproof to avoid loss of radioactivity into the laboratory environs not specifically protected by exhaust systems.
Xenon Xe 133 Gas adheres to some plastics and rubber and should not be allowed to stand in tubing or respirator containers. Loss of radioactivity due to such adherence may render the study nondiagnostic.
Directions for dispensing
Transfer the appropriate Xenon Xe 133 Gas dose from the Xenon Xe 133 Gas unit dose vial(s) to a breathing device or spirometer utilizing the Xenotron™ I Xenon Gas Dispenser. Follow the directions for use that are provided with the Xenotron™ I Xenon Gas Dispenser.
Xenon Xe 133 Gas should not be used after 14 days from the date of calibration stated on the label.
How is Xenon Xe 133 Gas Supplied
Xenon Xe 133 Gas is available in 2 milliliter vials with color-coded labels in 370 megabecquerel (10 millicurie; Catalog No. 097) and 740 megabecquerel (20 millicurie; Catalog No. 098) sizes. Both sizes are available in packages of 1, 3 and 5 vials, each with individual lead shielding.
PRINCIPAL DISPLAY PANEL -20 mCi
Xenon Xe 133 Gas
740 MBq (20 mCi)/vial
CAUTION RADIOACTIVE MATERIAL
Single Dose Container -Dispose in Accordance with Regulatory Requirements. For use with Xenotron™ I Xenon Gas Dispenser only.
Rx only
Mallinckrodt Nuclear Medicine LLC
A098V0
R05/2016
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| Labeler - MALLINCKRODT NUCLEAR MEDICINE LLC (079875617) |
For the Consumer
Applies to xenon xe-133: inhalation gas
Along with its needed effects, xenon xe-133 may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking xenon xe-133:
Incidence not known- Cough
- difficulty with swallowing
- dizziness
- fast heartbeat
- hives
- itching
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
- unusual tiredness or weakness
- wheezing
Xenon xe-133 Breastfeeding Warnings
Due to the potential for adverse reactions in nursing infants, formula feedings should be substituted for breast-feeding.
The manufacturer makes no recommendation regarding use during lactation. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: The effects in the nursing infant are unknown.
Administrative Information
LactMed Record Number
814
Last Revision Date
20160204
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.