X-Prep

Senna is used to relieve occasional constipation in adults and children. This medicine is a laxative. It generally produces bowel movement in 6 to 12 hours.

This medicine is available without your doctor's prescription.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Black, tarry stools
• blood in the stools
• nausea or vomiting
• stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Applies to senna: compounding powder, oral disintegrating strip, oral granule, oral liquid, oral syrup, oral tablet, oral tablet chewable, rectal suppository

Gastrointestinal

Gastrointestinal side effects have included esophageal impaction and duodenal bezoars. These effects have been reported in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (the active ingredient contained in X-Prep) (commercially available as Perdiem Overnight Relief).[Ref]

Hypersensitivity

Hypersensitivity side effects have rarely included occupational sensitization to senna (the active ingredient contained in X-Prep) [Ref]

One case has been reported involving a factory worker who developed IgE-mediated asthma and rhinoconjunctivitis five months after exposure to senna.[Ref]

Musculoskeletal

Musculoskeletal side effects have rarely included finger clubbing.[Ref]

Some side effects of X-Prep may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.