Voriconazole (Intravenous Route)

Voriconazole injection is used to treat certain serious fungal or yeast infections, such as aspergillosis (fungal infection in the lungs), candidemia (fungal infection in the blood), esophageal candidiasis (candida esophagitis), or other fungal infections (including infections in the skin, stomach, kidney, bladder, and wounds). It may also be used to treat patients with serious fungal or yeast infections who cannot tolerate other types of medicine or who do not respond to other types of medicine.

This medicine is to be given only by or under the direct supervision of your doctor.

This product is available in the following dosage forms:

• Powder for Solution

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Amifampridine
• Amisulpride
• Astemizole
• Bepridil
• Carbamazepine
• Cisapride
• Conivaptan
• Dihydroergotamine
• Dronedarone
• Efavirenz
• Eletriptan
• Eliglustat
• Eplerenone
• Ergoloid Mesylates
• Ergonovine
• Ergotamine
• Flibanserin
• Fluconazole
• Isavuconazonium Sulfate
• Ivabradine
• Lomitapide
• Lovastatin
• Lurasidone
• Maraviroc
• Mephobarbital
• Mesoridazine
• Methylergonovine
• Methysergide
• Naloxegol
• Nelfinavir
• Nimodipine
• Phenobarbital
• Pimozide
• Piperaquine
• Posaconazole
• Primidone
• Quinidine
• Rifabutin
• Rifampin
• Ritonavir
• Saquinavir
• Simvastatin
• Sirolimus
• Sparfloxacin
• St John's Wort
• Terfenadine
• Thioridazine
• Tolvaptan
• Venetoclax
• Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol
• Ado-Trastuzumab Emtansine
• Alprazolam
• Amiodarone
• Amitriptyline
• Amoxapine
• Anagrelide
• Apomorphine
• Aprepitant
• Aripiprazole
• Arsenic Trioxide
• Artemether
• Asenapine
• Avanafil
• Axitinib
• Azithromycin
• Bedaquiline
• Boceprevir
• Bosutinib
• Brentuximab Vedotin
• Bretylium
• Brexpiprazole
• Bromocriptine
• Buserelin
• Cabazitaxel
• Cabozantinib
• Calcifediol
• Cariprazine
• Ceritinib
• Chloramphenicol
• Chloroquine
• Chlorpromazine
• Cilostazol
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clomipramine
• Clozapine
• Cobicistat
• Cobimetinib
• Crizotinib
• Cyclobenzaprine
• Cyclosporine
• Dabrafenib
• Daclatasvir
• Dasabuvir
• Dasatinib
• Degarelix
• Delamanid
• Delavirdine
• Desipramine
• Deslorelin
• Dicumarol
• Disopyramide
• Docetaxel
• Dofetilide
• Dolasetron
• Domperidone
• Donepezil
• Doxorubicin
• Doxorubicin Hydrochloride Liposome
• Droperidol
• Elvitegravir
• Entacapone
• Enzalutamide
• Erlotinib
• Erythromycin
• Escitalopram
• Eslicarbazepine Acetate
• Eszopiclone
• Everolimus
• Fentanyl
• Fingolimod
• Flecainide
• Fluoxetine
• Fluticasone
• Fosaprepitant
• Fosphenytoin
• Gatifloxacin
• Gemifloxacin
• Glimepiride
• Gonadorelin
• Goserelin
• Granisetron
• Halofantrine
• Haloperidol
• Histrelin
• Hydrocodone
• Hydroxychloroquine
• Hydroxyzine
• Ibrutinib
• Ibutilide
• Idelalisib
• Ifosfamide
• Iloperidone
• Imipramine
• Irinotecan
• Irinotecan Liposome
• Ivacaftor
• Ixabepilone
• Lapatinib
• Leuprolide
• Levofloxacin
• Levomilnacipran
• Lopinavir
• Lumacaftor
• Lumefantrine
• Macitentan
• Manidipine
• Mefloquine
• Metronidazole
• Mifepristone
• Moxifloxacin
• Nafarelin
• Nevirapine
• Nifedipine
• Nilotinib
• Norfloxacin
• Nortriptyline
• Octreotide
• Ofloxacin
• Olaparib
• Ombitasvir
• Omeprazole
• Ondansetron
• Palbociclib
• Paliperidone
• Panobinostat
• Paritaprevir
• Pasireotide
• Pazopanib
• Perflutren Lipid Microsphere
• Phenprocoumon
• Phenytoin
• Pimavanserin
• Pitolisant
• Ponatinib
• Procainamide
• Prochlorperazine
• Promethazine
• Propafenone
• Protriptyline
• Quetiapine
• Quinine
• Ranolazine
• Reboxetine
• Regorafenib
• Retapamulin
• Romidepsin
• Ruxolitinib
• Salmeterol
• Sevoflurane
• Sildenafil
• Simeprevir
• Sodium Phosphate
• Sodium Phosphate, Dibasic
• Sodium Phosphate, Monobasic
• Solifenacin
• Sonidegib
• Sorafenib
• Sotalol
• Sulpiride
• Sunitinib
• Suvorexant
• Tacrolimus
• Tamsulosin
• Telaprevir
• Telavancin
• Telithromycin
• Temsirolimus
• Tetrabenazine
• Ticagrelor
• Tizanidine
• Toremifene
• Trabectedin
• Trazodone
• Triazolam
• Trifluoperazine
• Trimipramine
• Triptorelin
• Vandetanib
• Vardenafil
• Vemurafenib
• Vilanterol
• Vilazodone
• Vinblastine
• Vincristine
• Vincristine Sulfate Liposome
• Vinflunine
• Vinorelbine
• Vorapaxar
• Warfarin
• Zolpidem
• Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alfentanil
• Amprenavir
• Atorvastatin
• Cerivastatin
• Desogestrel
• Dienogest
• Drospirenone
• Esomeprazole
• Estradiol Cypionate
• Estradiol Valerate
• Ethinyl Estradiol
• Ethynodiol Diacetate
• Etonogestrel
• Etravirine
• Fosamprenavir
• Glipizide
• Glyburide
• Levonorgestrel
• Meloxicam
• Mestranol
• Methadone
• Midazolam
• Norelgestromin
• Norethindrone
• Norgestimate
• Norgestrel
• Oxycodone
• Tolbutamide
• Tretinoin

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cancer treatment (eg, chemotherapy), recent or history of or
• Heart disease, history of or
• Mineral imbalance (eg, low potassium, magnesium, or calcium in the blood) or
• Stem cell transplant—Use with caution. These conditions may increase your risk of having serious side effects.

• Heart rhythm problems (eg, arrhythmia, QT prolongation) or
• Liver disease (including cirrhosis) or
• Kidney disease or
• Pancreas problems—Use with caution. May make these conditions worse.