Verapamil Injection

Use verapamil injection as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• It is given as a shot into a vein.

What do I do if I miss a dose?

• Call your doctor to find out what to do.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
• Slow heartbeat.
• A new or worse heartbeat that does not feel normal.
• Very bad dizziness or passing out.
• Shortness of breath, a big weight gain, or swelling in the arms or legs.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Check with your pharmacist about how to throw out unused drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about verapamil injection, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about verapamil injection. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using verapamil injection.

Review Date: October 4, 2017

Verapamil hydrochloride injection is contraindicated in:

1. Severe hypotension or cardiogenic shock.

2. Second- or third-degree AV block (except in patients with a functioning artificial ventricular pacemaker).

3. Sick sinus syndrome (except in patients with a functioning artificial ventricular pacemaker).

4. Severe congestive heart failure (unless secondary to a supraventricular tachycardia amenable to verapamil therapy).

5. Patients receiving intravenous beta-adrenergic blocking drugs (e.g., propranolol). Intravenous verapamil and intravenous beta-adrenergic blocking drugs should not be administered in close proximity to each other (within a few hours), since both may have a depressant effect on myocardial contractility and AV conduction.

6.  Patients with atrial flutter or atrial fibrillation and an accessory bypass tract (e.g., Wolff- Parkinson-White, Lown-Ganong-Levine syndromes) are at risk to develop ventricular tachyarrhythmia including ventricular fibrillation if verapamil is administered. Therefore, the use of verapamil in these patients is contraindicated.

7. Ventricular tachycardia: Administration of intravenous verapamil to patients with wide-complex ventricular tachycardia (QRS ≥ 0.12 sec) can result in marked hemodynamic deterioration and ventricular fibrillation. Proper pretherapy diagnosis and differentiation from wide-complex supraventricular tachycardia is imperative in the emergency room setting.

8. Known hypersensitivity to verapamil hydrochloride.

NDC 0409-1144-02
Rx only

4 mL Single-dose

VERAPAMIL HCl Injection, USP
10 mg (2.5 mg/mL)

Hospira, Inc., Lake Forest, IL 60045 USA

Protect from light.
For IV use only.

RL-3282

2 mL Single-dose

NDC 0409-1144-05
Rx only

VERAPAMIL HCl
Injection, USP
5 mg/2 mL (2.5 mg/mL)

Protect from light. For IV use only.

RL-3249

Hospira, Inc., Lake Forest, IL 60045 USA

NDC 0409-4011-01

2 mL
VERAPAMIL HCl
Injection, USP
5 mg (2.5 mg/mL)

Protect from light.
For I.V. use only.

Rx only
RL-1873 (10/06)

Hospira, Inc.
Lake Forest, IL 60045 USA

Hospira

Verapamil HCl 10 mg/4 mL (2.5 mg/mL)

4 mL Single-dose syringe
NDC 0409-9633-05

Verapamil HCl Injection, USP
10 mg/4 mL (2.5 mg/mL)

Rx only

Protect From Light.

For Intravenous
use only.

RL-6823

Hospira

Hospira, Inc.
Lake Forest, IL 60045 USA