Trixaicin HP

• If you have an allergy to Trixaicin HP (capsaicin cream, gel, liquid, and lotion) or any part of this medicine.
• If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• If you are using another drug like this one.

This is not a list of all drugs or health problems that interact with Trixaicin HP.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Do not take Trixaicin HP by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
• Clean affected part before use. Make sure to dry well.
• You may wear gloves when putting on.
• Do not put on irritated skin.
• Do not put on cuts, scrapes, or damaged skin.
• Do not bathe, shower, or swim right after putting on.
• Do not put on right after a shower or bath.
• If this medicine gets in the eyes, rinse with cool water.
• Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
• Put a thin layer on the affected skin and rub in gently.
• If hands are treated, do not wash your hands for 30 minutes after you put on Trixaicin HP. Do not touch your eyes, nose, mouth, genitals, irritated skin, or contact lenses until you wash your hands.

What do I do if I miss a dose?

• If you use this medicine on a regular basis, put on a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not put on 2 doses or extra doses.
• Many times Trixaicin HP (capsaicin cream, gel, liquid, and lotion) is used on an as needed basis. Do not use more often than told by the doctor.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Trixaicin HP or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Trixaicin HP. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Applies to capsaicin topical: compounding powder, topical cream, topical film, topical gel, topical kit, topical liquid, topical lotion, topical stick

General

The most commonly reported side effects were application site erythema and application site pain.[Ref]

Local

Very common (10% or more): Application site erythema (63%), application site pain (42%)
Common (1% to 10%): Application site pruritus, application site papules, application site edema, application site swelling, application site dryness
Uncommon (0.1% to 1%): Application site urticaria, application site paresthesia, application site dermatitis, application site hyperesthesia, application site excoriation, application site warmth, application site anesthesia, application site bruising, application site inflammation, application site exfoliation[Ref]

Cardiovascular

Common (1% to 10%): Hypertension
Uncommon (0.1% to 1%): First degree atrio-ventricular (AV) block, tachycardia, palpitations, increased blood pressure[Ref]

Dermatologic

Uncommon (0.1% to 1%): Herpes zoster, pruritus
Frequency not reported: Abnormal skin odor, second degree burns[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis, bronchitis, sinusitis
Uncommon (0.1% to 1%): Cough, throat irritation
Frequency not reported: Sneezing, dyspnea, wheezing, exacerbation of asthma, irritation of the mucous membranes of the respiratory tract (such as nasal and throat irritation)[Ref]

Gastrointestinal

Common (1% to 10%): Nausea[Ref]

Musculoskeletal

Uncommon (0.1% to 1%): Pain in extremity, muscle spasms[Ref]

Nervous system

Uncommon (0.1% to 1%): Dysgeusia, hypoesthesia, burning sensation
Frequency not reported: Headache, peripheral sensory neuropathy, dizziness, dysgeusia, hyperesthesia[Ref]

Ocular

Uncommon (0.1% to 1%): Eye irritation
Frequency not reported: Irritation of the mucous membranes of the eyes, runny eyes[Ref]

Other

Frequency not reported: Peripheral edema[Ref]

Some side effects of Trixaicin HP may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.