Tolnaftate

Name: Tolnaftate

Tolnaftate Brand Names

Tolnaftate may be found in some form under the following brand names:

  • Absorbine Jr. Antifungal

  • Aftate

  • Atopalm Antifungal

  • Blis-To-Sol

  • Cidacin

  • Clarus

  • Desenex Spray

  • Dr. Scholl's Sport Spray

  • Footshield Plus

  • Fungatin

  • Fungi-Guard

  • Fungicure Gel

  • Fungifoam

  • Fungoid-D

  • FungusRx

  • Genaspor

  • hiVETIC

  • Hongo Killer Antifungal

  • Hongos

  • Lamisil Defense

  • Molecular AF

  • Mycocide

  • Mycocide NS

  • Np 27

  • Odor Eaters

  • Ongo-Fin

  • Podactin

  • Proclearz

  • Q-Naftate

  • T-Athlete

  • Tinactin

  • Tinaderm

  • Tinaspore

  • Tineacide

  • Ting

  • Tolnate

  • Uni-Sport

Tolnaftate Interactions

This is not a complete list of Tolnaftatedrug interactions. Ask your doctor or pharmacist for more information.

Cautions for Tolnaftate

Contraindications

  • Known hypersensitivity to tolnaftate or any ingredient in the formulation.a

Warnings/Precautions

Warnings

Administration Precautions

For external use only.109 110 111 Do not administer orally or intravaginally.a Avoid contact with nose, mouth, and other mucous membranes.109 110 111 a

Do not apply to eye.109 110 111 a If contact with the eye(s) occurs, wash with large amounts of water; consult a clinician if ocular irritation persists.a

Intentional misuse by deliberately concentrating and inhaling the contents of the aerosols can be harmful or fatal.111

Sensitivity Reactions

If irritation or hypersensitivity occurs, discontinue drug and consult clinician.109 110 111 a

Sensitization to butylated hydroxytoluene, which is present in some creams, solutions, and aerosol powder formulations, has been confirmed.a

Specific Populations

Pregnancy

Category C.112

Lactation

Safety not established.112

Pediatric Use

Should not be used in children <2 years of age unless otherwise directed by a clinician.109 110 111

Common Adverse Effects

Skin irritation.a

Stability

Storage

Topical

Cream

20–25°C.109 Avoid freezing.a

Powder and Solution

Store in tight containers at <40°C, preferably between 15–30°C.a Avoid freezing.a

Aerosol

2–30°C.a Do not use near fire or flame; do not expose to temperatures >49°C.111 a

Actions and Spectrum

  • Thiocarbamate antifungal structurally and pharmacologically unrelated to other commercially available antifungals.a

  • May be fungistatic or fungicidal against susceptible organisms.a

  • Mechanism of antifungal activity unknown.a Appears to distort the hyphae and stunt mycelial growth in susceptible fungi.a

  • Dermatophytes: Active in vitro against Epidermophyton floccosum, Microsporum audouinii, M. canis, M. gypseum, M. japonicum, Trichophyton mentagrophytes, T. rubrum, T. schoenleinii, and T. tonsurans.a

  • Inactive against Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus.a Inactive against bacteria, protozoa, and viruses.a

Advice to Patients

  • Importance of applying to affected areas as directed and avoiding contact with eyes, nose, mouth, or other mucous membranes.109 110 111

  • Importance of completing full course of treatment, even if symptoms improve.109 110 111 a

  • Importance of contacting clinician if improvement does not occur by end of prescribed treatment period.109 110 111 a

  • Importance of consulting clinician if treated area becomes irritated, blisters, swells, or oozes.109 110 111 a

  • Importance of informing clinicians of existing or contemplated therapy, including prescription and OTC drugs.109 110 111 a

  • Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed.109 110 111 a

  • Importance of informing patients of other important precautionary information.109 110 111 a (See Cautions.)

Uses

Consult your pharmacist.

How to use Tolnaftate Powder

Consult your pharmacist.

Side Effects

Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

List Tolnaftate Powder side effects by likelihood and severity.

Precautions

Consult your pharmacist.

Interactions

Consult your pharmacist.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

(web3)