Spironolactone (Oral Route)

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  • For edema:
    • Adults—At first, 100 milligrams (mg) per day, taken in either single or divided doses. Your doctor may adjust your dose if needed.
    • Children—Use and dose must be determined by your doctor.
  • For heart failure:
    • Adults—At first, 25 milligrams (mg) once a day. Your doctor may adjust your dose if needed and tolerated.
    • Children—Use and dose must be determined by your doctor.
  • For high blood pressure:
    • Adults—At first, 50 to 100 milligrams (mg) per day, taken in either single or divided doses. Your doctor may adjust your dose if needed.
    • Children—Use and dose must be determined by your doctor.
  • For low potassium in the blood:
    • Adults—25 to 100 milligrams (mg) per day.
    • Children—Use and dose must be determined by your doctor.
  • For too much aldosterone in the body:
    • Adults—400 milligrams (mg) for 4 days, or 400 mg per day for 3 to 4 weeks to diagnose the condition. Then, 100 to 400 mg per day after the diagnosis is confirmed.
    • Children—Use and dose must be determined by your doctor.