Restasis eent

Topical immunomodulator; systemic immunosuppressive agent.1 2 3 5 6 7 8 10

• Exact mechanism of action not fully elucidated, but thought to act as a partial immunomodulator with anti-inflammatory effects when administered topically to the eye.1 2 3 5 6 7 8 10

• Topical application to the eye reduces cell-mediated inflammatory responses associated with inflammatory ocular surface diseases.2 3

• Exhibits immunosuppressive activity when administered systemically.1

Restasis eye drops contain cyclosporine which is an immunosuppressant. Cyclosporine can increase tear production that has been reduced by inflammation in the eye(s).

Restasis eye drops are used to treat chronic dry eye that may be caused by inflammation.

Restasis ophthalmic emulsion may also be used for treating eye disease not listed in this medication guide.

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.

An overdose of Restasis is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

You should not put Restasis in your eyes while wearing contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses. It may be best not to wear contact lenses if you have dry eyes. Talk with your doctor.

Common side effects of Restasis include: burning sensation of eyes. See below for a comprehensive list of adverse effects.