Reteplase, recombinant Intravenous
Name: Reteplase, recombinant Intravenous
Before Using reteplase, recombinant
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For reteplase, recombinant, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to reteplase, recombinant or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of reteplase in the pediatric population. Safety and efficacy have not been established .
Geriatric
No information is available on the relationship of age to the effects of reteplase in geriatric patients. However, the risk of serious bleeding from reteplase, recombinant may be more likely in elderly patients .
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving reteplase, recombinant, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using reteplase, recombinant with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Defibrotide
Using reteplase, recombinant with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acenocoumarol
- Alteplase, Recombinant
- Anistreplase
- Apixaban
- Ardeparin
- Argatroban
- Aspirin
- Bemiparin
- Bivalirudin
- Certoparin
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Desirudin
- Edoxaban
- Enoxaparin
- Fondaparinux
- Heparin
- Lepirudin
- Nadroparin
- Parnaparin
- Pentosan Polysulfate Sodium
- Phenindione
- Phenprocoumon
- Protein C
- Reteplase, Recombinant
- Reviparin
- Rivaroxaban
- Streptokinase
- Tenecteplase
- Tinzaparin
- Urokinase
- Warfarin
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Other Medical Problems
The presence of other medical problems may affect the use of reteplase, recombinant. Make sure you tell your doctor if you have any other medical problems, especially:
- Bleeding problems or a history of bleeding in any part of the body or
- Blood vessel problems (aneurysm) or
- Brain disease or tumor or
- High blood pressure, uncontrolled or
- Stroke, history of or
- Surgery or injury to the brain or spine, recent—reteplase, recombinant should NOT be used in these conditions .
- Blood clots, history of or
- Diabetic eye problems (hemorrhagic retinopathy) or
- Heart infections (pericarditis, endocarditis) or
- Injections into a blood vessel or
- Kidney disease, severe or
- Liver disease, severe or
- Placement of any tube into the body or
- Surgery or injury of any kind, major and recent—The chance of serious bleeding may be increased .
- Heart rhythm problems—This condition may get worse.
- High cholesterol, history of—The chance of having a serious side effect may be increased .