Prostigmin Bromide
Name: Prostigmin Bromide
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Prostigmin Bromide Overview
Neostigmine methylsulfate is a prescription medication used to reverse the effects of nerve blocking drugs that are used during surgery. Neostigmine methylsulfate belongs to a group of drugs called cholinesterase inhibitors which help to increase a natural chemical in your body that stimulates muscle movement.
This medication is available in an injectable form to be given directly into a vein (IV) by a healthcare professional.
Common side effects include a slower heart beat, nausea, and vomiting.
Before Using Prostigmin Bromide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of neostigmine in the pediatric population. Safety and efficacy have not been established .
Geriatric
No information is available on the relationship of age to the effects of neostigmine in geriatric patients .
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Bupropion
- Donepezil
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Succinylcholine
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Intestine blockage (blocked gut or abdomen) or
- Kidney blockage (blocked urine flow) or
- Peritonitis (lining of the abdomen is inflamed)—Should not be used in patients with these conditions.
- Asthma or
- Bradycardia (slow heartbeat) or
- Heart attack, recent or
- Heart rhythm problems or
- Overactive thyroid or
- Seizures or
- Stomach ulcer—Use with caution. May make these conditions worse.