Potassium Chloride in Sodium Chloride

Potassium Chloride in Sodium Chloride Injection, USP is a sterile, nonpyrogenic, solution for fluid and electrolyte replenishment in a single dose container for intravenous administration. It contains no antimicrobial agents. Composition, osmolarity, pH and ionic concentration are shown in Table 1.

The flexible plastic container is fabricated from a specially formulated polyvinyl chloride (PL 146 Plastic). The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers.

Potassium Chloride in Sodium Chloride Injection, USP has value as a source of water and electrolytes. It is capable of inducing diuresis depending on the clinical condition of the patient.

Potassium Chloride in Sodium Chloride Injection, USP is indicated as a source of water and electrolytes.

Potassium Chloride in Sodium Chloride Injection, USP should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention.

Potassium Chloride in Sodium Chloride Injection, USP should be used with great care, if at all, in patients with hyperkalemia, severe renal failure and in conditions in which potassium retention is present.

The intravenous administration of Potassium Chloride in Sodium Chloride Injection, USP can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injection. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of the injection.

In patients with diminished renal function, administration of Potassium Chloride in Sodium Chloride Injection, USP may result in sodium or potassium retention.

Potassium salts should never be administered by IV push.

20 mEq POTASSIUM

1000 mL

NDC 0409-9257-39

POTASSIUM
CHLORIDE
in 0.45%
Sodium Chloride
Injection, USP
20
mEq

EACH 100 mL CONTAINS POTASSIUM CHLORIDE 149 mg;
SODIUM CHLORIDE 450 mg IN WATER FOR INJECTION.
ELECTROLYTES PER 1000 mL: POTASSIUM 20 mEq;
SODIUM 77 mEq; CHLORIDE; 97 mEq.
194 mOsmol/LITER (CALC.)
pH 4.8 (3.5 to 6.5)

ADDITIVES MAY BE INCOMPATIBLE. CONSULT WITH
PHARMACIST, IF AVAILABLE. WHEN INTRODUCING
ADDITIVES, USE ASEPTIC TECHNIQUE,
MIX THOROUGHLY AND DO NOT STORE.

SINGLE-DOSE CONTAINER. STORE AT 20 TO 25°C (68 TO
77°F). [SEE USP CONTROLLED ROOM TEMPERATURE.]
PROTECT FROM FREEZING. FOR I.V. USE.
USUAL DOSAGE: SEE INSERT.
STERILE, NONPYROGENIC. USE ONLY IF SOLUTION IS
CLEAR AND CONTAINER IS UNDAMAGED. MUST NOT BE
USED IN SERIES CONNECTIONS.

Rx ONLY

3
V
CONTAINS DEHP

PRINTED IN USA
IM-1673 (6/08)
HOSPIRA, INC., LAKE FOREST, IL 60045 USA

Hospira