Potassium Chloride Oral Solution

Potassium Chloride is indicated for the treatment and prophylaxis of hypokalemia in patients for whom dietary management with potassium-rich foods or diuretic dose reduction are insufficient.

Oral Solution 10%: 1.3 mEq potassium per mL.

Potassium chloride is contraindicated in patients on potassium sparing diuretics

Symptoms

The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired or if potassium is administered too rapidly potentially fatal hyperkalemia can result.

Hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5–8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-waves, depression of S-T segment, and prolongation of the QT-interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9–12 mEq/L).

Treatment

Treatment measures for hyperkalemia include the following:
1. Monitor closely for arrhythmias and electrolyte changes.
2. Eliminate foods and medications containing potassium and of any agents with potassium-sparing properties such as potassium-sparing diuretics, ARBS, ACE inhibitors, NSAIDS, certain nutritional supplements and many others.
3. Administer intravenous calcium gluconate if the patient is at no risk or low risk of developing digitalis toxicity.
4. Administer intravenously 300 to 500 mL/hr of 10% dextrose solution containing 10 to 20 units of crystalline insulin per 1000 mL.
5. Correct acidosis, if present, with intravenous sodium bicarbonate.
6. Use exchange resins, hemodialysis, or peritoneal dialysis.

In patients who have been stabilized on digitalis, too rapid a lowering of the serum potassium concentration can produce digitalis toxicity.

Potassium Chloride is a white crystalline or colorless solid. It is soluble in water and slightly soluble in alcohol. Chemically, Potassium Chloride is K-Cl with a molecular mass of 74.55.

Oral Solution: 10%: Each 15 mL of solution contains 1.5 g of potassium chloride, USP and the following inactive ingredients: citric acid anhydrous, FD&C Yellow #6, glycerin, methylparaben, natural/artificial orange flavor, propylene glycol, propylparaben, purified water, sodium citrate dihydrate, sucralose.

Potassium Chloride Oral Solution, is an orange solution available as follows:
(NDC# 66689-047-01), packaged in trays of 10 unit dose cups each.
NDC# 66689-047-30: Cases contains 30 unit dose cups of 15 mL
NDC# 66689-047-50: Cases contains 50 unit dose cups of 15 mL
NDC# 66689-047-80: Cases contains 80 unit dose cups of 15 mL
NDC# 66689-047-99: Cases contains 100 unit dose cups of 15 mL
(NDC# 66689-048-01), packaged in trays of 10 unit dose cups each.
NDC# 66689-048-30: Cases contains 30 unit dose cups of 30 mL
NDC# 66689-048-50: Cases contains 50 unit dose cups of 30 mL
NDC# 66689-048-80: Cases contains 80 unit dose cups of 30 mL
NDC# 66689-048-99: Cases contains 100 unit dose cups of 30 mL

Storage
Store at Controlled Room Temperature, 25°C (77°F); excursions are permitted to 15° - 30°C (59° - 86°F).
Dispense in a tight, light-resistant container as defined in the USP PROTECT from LIGHT.

KEEP THIS AND ALL MEDICATION OUT OF THE REACH OF CHILDREN.

Rx only

Manufactured by:
Vistapharm Inc.
Largo, FL 33771

VP2146R2
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