Poly Hist CB
Name: Poly Hist CB
Poly Hist CB Overview
Poly Hist CB is a brand name medication included in the following groups of medications: Other cough suppressants, Expectorants. For more information about Poly Hist CB see its generics Guaifenesin, Pentoxyverine
Clinical Pharmacology
Carbetapentane citrate is a centrally acting non-narcotic antitussive.
Guaifenesin is an expectorant. Its action increases the output of respiratory tract fluid by reducing
adhesiveness and surface tension. Sinus and bronchial drainage is improved and dry, nonproductive
coughs become more productive and less frequent.
Guaifenesin is an expectorant. Its action increases the output of respiratory tract fluid by reducing
adhesiveness and surface tension. Sinus and bronchial drainage is improved and dry, nonproductive
coughs become more productive and less frequent.
Carcinogenesis, Mutagenesis, And Impairment of Fertility
No adequate and well controlled studies have been conducted to determine whether the components
of Poly Hist CB have a potential for carcinogenesis, mutagenesis, or impairment of fertility.
of Poly Hist CB have a potential for carcinogenesis, mutagenesis, or impairment of fertility.
Overdosage
SIGNS AND SYMPTOMS: Incidence of acute toxicity with guaifenesin is low and over dosage
is unlikely to produce serious toxic effects. In laboratory animals no toxicity resulted when
guaifenesin was administered by stomach tube in doses up to 5 grams/kg.
TREATMENT: Treatment of the signs and symptoms of overdosage is symptomatic and
supportive. The patient should be induced to vomit, even if emesis has occurred spontaneously.
Pharmacologic vomiting by the administration of ipecac syrup is a preferred method, however,
vomiting should not be induced in patients with impaired consciousness. Precautions against
aspiration must be taken, especially in infants and children. Following emesis, any drug
remaining in the stomach may be absorbed by activated charcoal administered as a slurry with water.
is unlikely to produce serious toxic effects. In laboratory animals no toxicity resulted when
guaifenesin was administered by stomach tube in doses up to 5 grams/kg.
TREATMENT: Treatment of the signs and symptoms of overdosage is symptomatic and
supportive. The patient should be induced to vomit, even if emesis has occurred spontaneously.
Pharmacologic vomiting by the administration of ipecac syrup is a preferred method, however,
vomiting should not be induced in patients with impaired consciousness. Precautions against
aspiration must be taken, especially in infants and children. Following emesis, any drug
remaining in the stomach may be absorbed by activated charcoal administered as a slurry with water.