Podophyllum Resin
Name: Podophyllum Resin
Dosing & Uses
Dosage Forms & Strengths
solution
- 25%
Condyloma Acuminata
Thoroughly cleanse area
Use supplied aplicator to apply thoroughly to lesion; allow to dry thoroughly; leave first application in contact for only a few minutes (30-40 min) to test for sensitivity
Leave on subsequent applications for 1-4 hr depending on condition of lesion and patient
Protect adjacent normal skin with petrolatum
Remove dried podophyllin thoroughly with alcohol or soap and water after treatment time has elapsed
Dosage Forms & Strengths
solution
- 25%
Condyloma Acuminata
Thoroughly cleanse area
Use supplied aplicator to apply thoroughly to lesion; allow to dry thoroughly; leave first application in contact for only a few minutes (30-40 min) to test for sensitivity
Leave on subsequent applications for 1-4 hr depending on condition of lesion and patient
Protect adjacent normal skin with petrolatum
Remove dried podophyllin thoroughly with alcohol or soap and water after treatment time has elapsed
Adverse Effects
Frequency Not Defined
Local
- Severe necrosis/scarring of the anogenital area
- Paraphimosis
- Pseudoepitheliomatous hyperplasia
Systemic
- Urticaria
- Fever
- Paresthesia
- Polyneuritis
- Paralytic ileus
- Pyrexia leukopenia
- Thrombocytopenia
- Coma
Patient Handout
Introduction
Antimitotic; caustic agent.100 117 118
Interactions for Podophyllum Resin
Specific Drugs
| Drug | Interaction | Comments |
|---|---|---|
| Corticosteroids | Concomitant use contraindicated100 a |
Preparations
Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.
Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.
* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name
| Routes | Dosage Forms | Strengths | Brand Names | Manufacturer |
|---|---|---|---|---|
| Bulk | Powder* | |||
| Topical | Solution | 25% | Podocon-25 (in compound benzoin tincture) | Paddock |