Pediox

Carbinoxamine is a prescription medication used to treat runny nose, stuffy nose, watery eyes, and itching caused by hay fever, seasonal and perennial allergies, and other allergic conditions. Carbinoxamine belongs to a group of drugs called antihistamines, which work by stopping the action of histamines, a substance produced in the body to react to foreign substances.

This medication comes in an extended-release oral suspension (liquid) form to be taken by mouth, once every 12 hours. It may be taken with or without food.

Common side effects of carbinoxamine include sleepiness, dizziness, loss of coordination, stomach irritation, and thickening of mucus. Do not drive or operate heavy machinery until you know how carbinoxamine affects you.

Serious side effects have been reported with carbinoxamine. See “Drug Precautions” section.

Common side effects of carbinoxamine include:

• sleepiness
• dizziness
• loss of coordination
• stomach irritation
• thickening of mucus.

Alcohol may intensify some of the side effects of this medication.

This is not a complete list of carbinoxamine side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Take carbinoxamine exactly as prescribed.
• The dose of carbinoxamine should be individualized based on the severity of the condition and the response of the patient. Start with lower doses and increase as needed and tolerated. 

• Give carbinoxamine by the orally (by mouth) only. Measure carbinoxamine with an accurate milliliter-measuring device. A household teaspoon is not an accurate measuring device and could lead to overdosage. A pharmacist can provide an appropriate measuring device and can provide instructions for measuring the correct dose.
• If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of carbinoxamine at the same time.

If you take too much carbinoxamine, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Store carbinoxamine ER suspension at room temperature.

Dispense in tight, light-resistant container with child-resistant closure.

Keep this and all medicines out of the reach of children.

In the U.S.

• Arbinoxa
• Carbihist
• Carboxine
• Histex CT
• Histex I/E
• Histex PD
• Histuss PD
• Karbinal ER
• Mintex PD
• Palgic
• Pediatex
• Pediox

Available Dosage Forms:

• Suspension, Extended Release
• Suspension
• Solution
• Tablet
• Liquid
• Tablet, Extended Release
• Capsule, Extended Release

Therapeutic Class: Respiratory Agent

Pharmacologic Class: Carbinoxamine

Chemical Class: Carbinoxamine

Carbinoxamine is used to treat symptoms of seasonal (short-term) or perennial (long-term) allergies, such as sneezing, runny nose, itching, watery eyes, hives, skin rash, itching, or wheezing. It is also used to treat symptoms of allergic rhinitis, allergic conjunctivitis caused by inhaled allergens and foods, or allergic skin reactions. This medicine is an antihistamine.

Carbinoxamine is used with epinephrine to treat severe allergic reactions (anaphylaxis). It is also used to treat allergic reactions to blood or plasma.

This medicine is available only with your doctor's prescription.

This section provides information on the proper use of a number of products that contain carbinoxamine. It may not be specific to Pediox. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often, unless otherwise directed by your doctor.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The teaspoons and tablespoons that are used for serving and eating food do not measure exact amounts.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (extended-release suspension):
  • For treatment of allergies:
    • Adults and children 12 years of age and older—6 to 16 milligrams (mg) every 12 hours. Your doctor may adjust your dose as needed.
    • Children 6 to 11 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 12 mg every 12 hours. Your doctor may adjust your dose as needed.
    • Children 4 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 3 to 8 mg every 12 hours. Your doctor may adjust your dose as needed.
    • Children 2 to 3 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 3 to 4 mg every 12 hours. Your doctor may adjust your dose as needed.
    • Children younger than 2 years of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

If you will be taking this medicine for a long time, it is very important that your doctor check you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.

Do not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate®.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert and not able to think well.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures or barbiturates; muscle relaxants, or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.