Ospemifene (Oral Route)

Name: Ospemifene (Oral Route)

US Brand Name

  1. Osphena

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ospemifene in the elderly.

Pregnancy

Information about this ospemifene-oral-route
Pregnancy Category Explanation
All Trimesters X Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abiraterone
  • Amiodarone
  • Bupropion
  • Ceritinib
  • Clarithromycin
  • Eliglustat
  • Eslicarbazepine Acetate
  • Fluconazole
  • Fluvoxamine
  • Idelalisib
  • Ketoconazole
  • Piperaquine
  • Regorafenib

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amobarbital
  • Aprobarbital
  • Bosentan
  • Butabarbital
  • Butalbital
  • Carbamazepine
  • Dexamethasone
  • Efavirenz
  • Enzalutamide
  • Etravirine
  • Fosphenytoin
  • Mephobarbital
  • Methohexital
  • Modafinil
  • Nafcillin
  • Nevirapine
  • Oxcarbazepine
  • Pentobarbital
  • Phenobarbital
  • Phenytoin
  • Prednisone
  • Primidone
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Secobarbital
  • St John's Wort
  • Thiopental

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For dyspareunia:
      • Adults—60 milligrams (mg) once a day.
      • Children—Use is not recommended.
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