Omeprazole Oral Capsule, Sprinkles

Omeprazole oral capsules sprinkles can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Drugs you should not use with omeprazole

Do not take these drugs with omeprazole. Doing so can cause dangerous effects in the body. Examples of these drugs include:

• Atazanavir and nelfinavir. Omeprazole may greatly decrease the effects of these drugs and could make them less effective over time. You shouldn’t take these drugs with omeprazole.

Interactions that increase the risk of side effects

• Side effects from omeprazole: Taking omeprazole with certain medications raises your risk of side effects from omeprazole. This is because the amount of omeprazole in your body is increased. Examples of these drugs include:
  • Voriconazole. This drug may increase the levels of omeprazole in your body. If you’re taking high doses of omeprazole, your doctor may adjust your omeprazole dose.
• Side effects from other drugs: Taking omeprazole with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:
  • Saquinavir. Omeprazole may greatly increase the levels of saquinavir in your body. Your doctor may lower your dose of saquinavir.
  • Digoxin. Omeprazole may increase the levels of digoxin in your body. Your doctor may monitor the levels of digoxin in your blood.
  • Warfarin. Omeprazole may increase the levels of warfarin in your body. Your doctor may monitor you for symptoms of bleeding.
  • Phenytoin. Omeprazole may increase the levels of phenytoin in your body. Your doctor may watch you for high levels of phenytoin.
  • Cilostazol. Omeprazole may increase the levels of cilostazol in your body. Your doctor may lower your dose of cilostazol.
  • Tacrolimus. Omeprazole may increase the levels of tacrolimus in your body. Your doctor may monitor the level of tacrolimus in your body.
  • Methotrexate. Omeprazole may increase the effects of methotrexate. Your doctor may adjust your dose depending on the levels of methotrexate in your body.
  • Diazepam. Omeprazole may increase the levels of diazepam in your body. Your doctor may watch you for more side effects from diazepam.
  • Benzodiazepines. Your doctor will monitor you while you’re taking these drugs with omeprazole. Your doctor may change your dose.

Interactions that can make your drugs less effective

• When other drugs are less effective: When certain drugs are used with omeprazole, they may not work as well. This is because the amount of these drugs in your body may be decreased. Examples of these drugs include:
  • Ampicillin esters. Omeprazole can keep your body from absorbing antibiotics like ampicillin well. Ampicillin may not work as well to treat your infection.
  • Ketoconazole. Omeprazole can keep your body from absorbing ketoconazole well. Ketoconazole may not work as well to treat your infection.
  • Mycophenolate mofetil (MMF). Omeprazole can keep your body from absorbing MMF well. MMF may not work as well. It isn’t known how this may affect your risk of organ rejection. If you take MMF, ask your doctor if dexlansoprazole is safe for you to take.
  • Iron salts. Omeprazole can keep your body from fully absorbing drugs that contain iron.
  • Erlotinib. Omeprazole can keep your body from absorbing erlotinib well. Erlotinib may not work as well to treat your cancer.
  • Clopidogrel. Omeprazole may make clopidogrel work less well.
• When omeprazole is less effective: When omeprazole is used with certain drugs, it may not work as well to treat your condition. This is because the amount of omeprazole in your body may be decreased. Examples of these drugs include:
  • St. John’s wort
  • Rifampin

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.