Norditropin FlexPro Pen

You should not use this medicine if you are allergic to somatropin or benzyl alcohol, or if you have:

• a serious illness due to lung failure or complications from recent surgery, injury, or medical trauma;

• cancer;

• eye problems caused by diabetes (diabetic retinopathy); or

• if you are being treated for Prader-Willi syndrome and you are overweight or have severe breathing problems (including sleep apnea).

To make sure somatropin is safe for you, tell your doctor if you have:

• diabetes;

• a pituitary gland disorder;

• abnormal curvature of the spine (scoliosis);

• underactive thyroid;

• history of head injury or brain tumor; or

• a history of childhood brain cancer and radiation treatment.

Some brands of somatropin are not expected to harm an unborn baby, including Genotropin, Omnitrope, Saizen, Serostim, and Zorbtive.

It is not known whether certain other brands of somatropin will harm an unborn baby, including Humatrope, Norditropin, Nutropin, and Tev-tropin.

Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether somatropin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

If you use Zorbtive to treat short bowel syndrome, avoid drinking fruit juices or soda beverages. Follow the instructions of your doctor or nutrition counselor about what types of liquids you should drink while using Zorbtive.

Avoid drinking alcohol if you have short bowel syndrome. Alcohol can irritate your stomach and could make your condition worse.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Serious breathing problems may occur in patients with Prader-Willi syndrome who use somatropin. If you have Prader-Willi syndrome, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or increased snoring.

Also call your doctor at once if you have:

• vision changes with sudden and severe pain behind your eyes and nausea or vomiting;

• pain in your knees or hips, or walking with a limp;

• ear pain, swelling, warmth, or drainage;

• numbness or tingling in your wrist, hand, or fingers;

• severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; or

• high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss.

Common side effects may include:

• swelling, rapid weight gain;

• muscle or joint pain;

• headache; or

• pain, itching, or skin changes where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your current medicines and any you start or stop using, especially:

• birth control pills or hormone replacement therapy

• insulin or oral diabetes medicine; or

• steroid medicine (prednisone, dexamethasone, methylprednisolone, and others).

This list is not complete. Other drugs may interact with somatropin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.