Nintedanib (Oral Route)

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nintedanib in the elderly.

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Tobacco

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems, history of or
• Diarrhea or
• Nausea or
• Vomiting—Use with caution. May make these conditions worse.

• Blood clots, history of or
• Coronary artery disease or
• Heart attack, recent or
• Heart disease or
• Stomach or abdominal surgery, recent or
• Stroke, history of—Use with caution. May cause side effects to become worse.

• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.