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Clotrimazole is a prescription and over-the-counter medication used to treat yeast infections of the vagina, mouth, and skin. Clotrimazole can also be used to prevent yeast infection in the mouth in certain patients.

Clotrimazole is both an over-the-counter and a prescription medication. The over-the-counter forms are used to treat yeast infections of the skin and the vagina. The prescription forms are used to treat yeast infections of the mouth and skin. This medication page refers to the prescription forms of clotrimazole.

Clotrimazole belongs to a group of drugs called antifungals. These work by inhibiting the growth of infection-causing yeast.

This medication comes in a topical solution, a topical cream, and a lozenge form. How often this medication is used will change, depending on the indication for use.

Common side effects of clotrimazole include redness, stinging, blistering, peeling, swelling, itching, burning, and irritation at the site of application. Stomach upset and vomiting may occur with the oral lozenge.

• Bayer Pharmaceuticals Corporation

• Ortho-McNeil Pharmaceutical Corporation

• Quality Care Pharmaceuticals

No drug interactions have been reported by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Before using clotrimazole, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

• are allergic to clotrimazole or to any of its ingredients
• have liver disease
• have a compromised immune system
• have diabetes
• drink alcohol or have a history of alcohol abuse
• are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Use clotrimazole exactly as prescribed.

Topical cream and solution:

Clotrimazole comes in topical cream and solution forms and is applied to affected skin twice daily, in the morning and evening, to treat yeast infections of the skin.

Oral lozenges:

Clotrimazole comes in an oral lozenge and is used five times daily for the treatment of yeast infections of the mouth. For prevention of yeast infections of the mouth, the lozenges are used three times daily.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not use two doses of clotrimazole at the same time.

If you use too much clotrimazole, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If clotrimazole is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.