Mineral Oil

Constipation

Relief of occasional constipation.a e f

Relief of constipation associated with stricture of the colon and for softening fecal impactions.d

Bulk-forming laxatives, stool softeners, or mineral oil are preferred to other laxatives when a soft stool is desired, especially in patients with conditions in which straining during defecation should be avoided (e.g., MI, hypertension, vascular diseases, diseases of the anus or rectum, hernias, recent rectal or abdominal surgery).c d

Mineral oil may be preferred to bulk-forming laxatives to ease evacuation of feces in patients with constipation associated with hard, dry stools.c

Has been used in fixed combination with a saline laxative (magnesium hydroxide).f

Colonic Evacuation

Used as an enema to empty the colon prior to surgery or radiologic or colonoscopic procedures.c

Used as an enema to remove barium sulfate residues from the colon after barium administration.e

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Mineral Oil

intestinal lubricant

keep tightly closed

protect from sunlight

(MIN er al oyl)

• Heavy Mineral Oil
• Liquid Paraffin
• White Mineral Oil

• Laxative, Lubricant

Constipation:

Oral:

Manufacturer’s labeling:

Children 6 to <12 years:

Plain (nonemulsified) liquid: 5 to 15 mL in 24 hours (maximum: 15 mL in 24 hours). May be taken as a single dose (at bedtime) or in divided doses.

Suspension (emulsion) (Kondremul): 10 to 30 mL daily (maximum: 30 mL daily). May be taken as a single dose or divided in up to 3 equal divided doses.

Children ≥12 years and Adolescents: Refer to adult dosing.

Alternate recommendations: Children and Adolescents: 1 to 3 mL/kg/day once daily or divided in 2 doses; maximum daily dose: 90 mL/day (NASPGHAN [Tabbers 2014])

Rectal (Fleet Mineral Oil):

Manufacturer’s labeling:

Children 2 to <12 years: 59 mL as a single dose

Children ≥12 years: Refer to adult dosing.

Alternate recommendations:

Children 2 to 11 years: 30 to 60 mL once daily (NASPGHAN [Tabbers 2014])

Children ≥12 years and Adolescents: 60 to 150 mL once daily (NASPGHAN [Tabbers 2014])

Fecal impaction or following barium studies: Rectal (Fleet Mineral Oil):

Children 2 to <12 years: 59 mL as a single dose

Children ≥12 years and Adolescents: Refer to adult dosing.

Frequency not defined.

Gastrointestinal: Abdominal cramps, diarrhea, nausea, oily rectal leakage (large doses; may cause anal irritation, hemorrhoids, perianal discomfort, pruritus ani, soiling of clothes), vomiting

Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.