Micafungin

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Other drugs may interact with micafungin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Call your doctor for instructions if you miss a dose of micafungin.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
• Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
• Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
• Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
• A fast heartbeat.
• Any unexplained bruising or bleeding.
• Feeling very tired or weak.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

• Micafungin Sodium

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution Reconstituted, Intravenous, as sodium:

Mycamine: 50 mg (1 ea); 100 mg (1 ea)

Solution Reconstituted, Intravenous, as sodium [preservative free]:

Mycamine: 50 mg (1 ea); 100 mg (1 ea)

• Mycamine

• Antifungal Agent, Parenteral
• Echinocandin

Refer to adult dosing.

Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Reconstituted and diluted solutions in D5W or NS are stable for 24 hours at room temperature. Protect infusion solution from light (it is not necessary to protect the drip chamber or tubing from light).

4 months or older: 2 mg/kg via IV infusion once a day
Maximum dose: 100 mg per day

Comments:
-Not adequately studied in patients with endocarditis, osteomyelitis, and meningitis due to Candida infections.

Approved indications: Treatment of patients with candidemia, acute disseminated candidiasis, Candida peritonitis and abscesses

No adjustment recommended.