Metipranolol Ophthalmic

Temporary discomfort of the eye, blurred vision, watery eyes, headache, drowsiness, or dizziness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: eye pain/swelling/discharge, increased eye sensitivity to light, vision changes, slow/irregular heartbeat, muscle weakness, mental/mood changes, tiredness, swelling of the ankles/feet, sudden/unexplained weight gain.Seek immediate medical attention if any of these rare but very serious side effects occur: trouble breathing, chest/jaw/left arm pain, weakness on one side of the body, slurred speech, confusion.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. If this product is accidentally swallowed, you may experience symptoms such as trouble breathing, slow/irregular heartbeat.

In the U.S.

• Optipranolol

Available Dosage Forms:

• Solution

Therapeutic Class: Antiglaucoma

Pharmacologic Class: Beta-Adrenergic Blocker, Nonselective

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not determined

• Bloody nose
• blurred vision
• burning, dry, or itching eyes
• changes in vision
• chest pain or discomfort
• cough producing mucus
• difficult or labored breathing
• difficulty in moving
• difficulty seeing at night
• difficulty swallowing
• discharge, excessive tearing
• fast, slow, irregular, pounding, or racing heartbeat or pulse
• headache
• hives
• increased sensitivity of eyes to sunlight
• itching
• lightheadedness, dizziness, or fainting
• muscle pain or stiffness
• nausea
• nervousness
• pain in forehead
• pain or discomfort in arms, jaw, back, or neck
• pain, swelling, or redness in joints
• pounding in the ears
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness, pain, swelling, or itching of the eye, eyelid, or inner lining of eyelid
• shortness of breath
• skin rash
• sweating
• tightness in chest
• unusual tiredness or weakness
• wheezing
• vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Confusion
• dilated neck veins
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• extreme fatigue
• irregular breathing
• swelling of face, fingers, feet, or lower legs
• weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined

• Discouragement
• feeling sad or empty
• irritability
• lack of appetite
• lack or loss of strength
• loss of interest or pleasure
• muscle aching or cramping
• runny nose
• sleepiness or unusual drowsiness
• sneezing
• stuffy nose
• tiredness
• trouble concentrating
• trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

Metipranolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Metipranolol ophthalmic is sometimes given together with other eye medications. Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using metipranolol ophthalmic. Do not use the medications at the same time.

Applies to metipranolol ophthalmic: ophthalmic solution

Along with its needed effects, metipranolol ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking metipranolol ophthalmic:

Incidence not determined

• Bloody nose
• blurred vision
• burning, dry, or itching eyes
• changes in vision
• chest pain or discomfort
• cough producing mucus
• difficult or labored breathing
• difficulty in moving
• difficulty seeing at night
• difficulty swallowing
• discharge, excessive tearing
• fast, slow, irregular, pounding, or racing heartbeat or pulse
• headache
• hives
• increased sensitivity of eyes to sunlight
• itching
• lightheadedness, dizziness, or fainting
• muscle pain or stiffness
• nausea
• nervousness
• pain in forehead
• pain or discomfort in arms, jaw, back, or neck
• pain, swelling, or redness in joints
• pounding in the ears
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness, pain, swelling, or itching of the eye, eyelid, or inner lining of eyelid
• shortness of breath
• skin rash
• sweating
• tightness in chest
• unusual tiredness or weakness
• wheezing
• vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking metipranolol ophthalmic:

Symptoms of overdose

• Confusion
• dilated neck veins
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• extreme fatigue
• irregular breathing
• swelling of face, fingers, feet, or lower legs
• weight gain

Some side effects of metipranolol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined

• Discouragement
• feeling sad or empty
• irritability
• lack of appetite
• lack or loss of strength
• loss of interest or pleasure
• muscle aching or cramping
• runny nose
• sleepiness or unusual drowsiness
• sneezing
• stuffy nose
• tiredness
• trouble concentrating
• trouble sleeping

One drop in the affected eye(s) twice a day

Comments:
-If intraocular pressure is not at a satisfactory level on this regimen, use of more frequent administration or a larger dose is not known to be of benefit.
-Concomitant therapy to lower intraocular pressure can be initiated with pilocarpine, epinephrine, or acetazolamide.

Use: Treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma

Data not available

This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus. US FDA pregnancy category: C

Animal studies have shown an increase in fetal resorption, fetal death, and delayed development when administered orally. There are no adequate and well-controlled studies in pregnant women. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.