Ketorolac Ophthalmic

Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

In the U.S.

• Acular
• Acular LS
• Acular PF
• Acuvail

In Canada

• Apo-Ketorolac
• Ratio-Ketorolac

Available Dosage Forms:

• Solution

Therapeutic Class: Ophthalmologic Agent

Pharmacologic Class: Ketorolac

Chemical Class: Ketorolac

Ketorolac eye drops is used to treat itching caused by seasonal allergic conjunctivitis (an allergy that occurs at only certain times of the year). It is also used to treat pain, burning, and inflammation of the eye following cataract surgery or corneal refractive surgery. ketorolac is a topical nonsteroidal anti-inflammatory drug (NSAID).

ketorolac is available only with your doctor's prescription.

Your eye doctor will tell you how much of ketorolac to use and how often. Do not use more medicine or use it more often than your doctor tells you to. ketorolac is not for long-term use.

ketorolac can be used with other ophthalmic (eye) medicines. Wait at least 5 minutes before using another eye medicine.

If you or your child are wearing contact lenses, remove them while you are using ketorolac. Talk to your eye doctor about this if you have questions.

If you are using ketorolac after an eye surgery, use one bottle for each eye only. Use of the same bottle of eye drops for both eyes is not recommended.

To use the eye drops:

• First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed by the eye.
• Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.
• If you think you did not get the drop of medicine into your eye properly, use another drop.
• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, always keep the container tightly closed.

Dosing

The dose of ketorolac will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of ketorolac. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For ophthalmic dosage form (eye drops):
  • For relief of eye itching caused by seasonal allergic conjunctivitis:
    • Adults and children 2 years of age and older—Use one drop in the affected eye(s) 4 times a day.
    • Children younger than 2 years of age—Use and dose must be determined by your doctor.
  • For eye swelling following cataract surgery:
    • Adults and children 2 years of age and older—Use one drop in the affected eye(s) 4 times a day beginning 24 hours after surgery and for 2 weeks after the surgery.
    • Children younger than 2 years of age—Use and dose must be determined by your doctor.
  • For eye pain, burning, or stinging following corneal refractive surgery:
    • Adults and children 3 years of age and older—Use one drop in the affected eye(s) 4 times a day for up to 4 days after the surgery.
    • Children younger than 3 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of ketorolac, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

(KEE toe role ak)

Postoperative ocular inflammation following cataract extraction (0.5% solution): Children ≥2 years and Adolescents: Refer to adult dosing.

Postoperative ocular pain following corneal refractive surgery (0.4% solution): Children ≥3 years and Adolescents: Refer to adult dosing.

Seasonal allergic conjunctivitis (ocular itching) (0.5% solution): Children ≥2 years and Adolescents: Refer to adult dosing.

There are no dosage adjustments provided in the manufacturer’s labeling.

Corticosteroids (Ophthalmic): NSAID (Ophthalmic) may enhance the adverse/toxic effect of Corticosteroids (Ophthalmic). Healing of ophthalmic tissue during concomitant administration of ophthalmic products may be delayed. Exceptions: Loteprednol. Monitor therapy

Adverse events have been observed in animal reproduction studies. Systemic exposure is decreased with ophthalmic administration (concentrations are ~4% to 8% of the minimum plasma concentration following an oral dose). If ophthalmic agents are needed during pregnancy, the minimum effective dose should be used in combination with punctual occlusion to decrease potential exposure to the fetus (Samples 1988). However, because it may cause prenatal constriction of the ductus arteriosus, the manufacturer recommends that the use of ketorolac ophthalmic drops late in pregnancy be avoided.

While using this medication, do not wear any contact lens that has not been approved by your doctor.

Do not use other eye medications unless your doctor tells you to.