Ketorolac Nasal Spray

Nasal ketorolac comes as a liquid to spray in the nose. It is usually used once every 6 to 8 hours as needed to control pain for up to 5 days. Use ketorolac nasal spray exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Ketorolac nasal spray comes in bottles that each contain a one-day supply of medication. Do not use any single bottle of ketorolac nasal spray for more than one day. Dispose of the bottle within 24 hours of using the first dose, even if the bottle still contains some medication. You will receive enough bottles of medication so that you have a new bottle to use for each day of treatment.

Before you use ketorolac nasal spray for the first time, read the written instructions that come with the medication. Be sure that you understand how to prepare the bottle before the first use and how to use the spray. Ask your doctor or pharmacist if you have any questions about how to use this medication.

Ketorolac nasal spray is only for use in the nose. Be careful not to get the medication in your eyes. If you do get ketorolac nasal spray in your eye, wash out the eye with water or sterile saline solution and call your doctor if irritation lasts longer than an hour.

You may have an uncomfortable feeling in your throat after you use ketorolac nasal spray. If this happens, drink a sip of water.

Before using ketorolac nasal spray,

• Tell your doctor if you are allergic to ketorolac, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) or naproxen (Aleve, Naprosyn), any other medications, or ethylendiamine tetraacetic acid (EDTA; an ingredient found in some foods and medications), or any of the other ingredients in ketorolac nasal spray. Ask your pharmacist for a list of the ingredients.
• tell your doctor if you are taking pentoxifylline (Pentoxil, Trental) or probenecid. Your doctor will probably tell you not to use ketorolac nasal spray if you are taking these medications.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: alprazolam (Niravam, Xanax);carbamazepine (Epitol, Tegretol); lithium (Eskalith, Lithobid);methotrexate (Rheumatrex, Trexall); phenytoin (Dilantin, Phenytek);or thiothixene (Navane). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had the conditions listed in the IMPORTANT WARNING section or asthma, especially if you also have frequent stuffed or runny nose or nasal polyps (swelling of the lining of the nose), inflammatory bowel disease such as Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) or ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum).
• tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or you plan to become pregnant. Ketorolac may cause serious harm to the fetus when taken in the last few months of pregnancy. If you become pregnant while using ketorolac nasal spray, call your doctor.
• Do not breastfeed during your treatment with ketorolac nasal spray.
• If you are having surgery, including dental surgery, tell the doctor or dentist that you are using ketorolac nasal spray.

Make sure you drink plenty of fluids while using ketorolac nasal spray.

Unless your doctor tells you otherwise, continue your normal diet.

This medication is usually used as needed. If your doctor has told you to use ketorolac nasal spray regularly, use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include the following:

• stomach pain
• nausea
• vomiting
• decreased urination
• bloody, black, or tarry stools
• vomit that is bloody or looks like coffee grounds
• drowsiness
• slowed breathing
• coma (loss of consciousness for a period of time)

• Sprix^®