Homatropine and hydrocodone

You should not use this medicine if you are allergic to homatropine or hydrocodone.

Some medicines can interact with hydrocodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure homatropine and hydrocodone is safe for you, tell your doctor if you have:

• severe asthma or breathing problems;

• a history of head injury, brain tumor, or seizures;

• liver or kidney disease;

• Addison's disease;

• underactive thyroid;

• enlarged prostate or urination problems;

• glaucoma;

• stomach problems; or

• if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).

It is not known whether this medicine will harm an unborn baby. If you use hydrocodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether homatropine and hydrocodone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Homatropine and hydrocodone is not approved for use by anyone younger than 6 years old.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A hydrocodone overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pale skin, blue-colored lips, and fainting.

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with hydrocodone.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how homatropine and hydrocodone will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Usual Adult Dose for Cough:

5 mL of syrup (1.5 mg-5 mg/5 mL) or I tablet (1.5 mg-5 mg) orally every 4 to 6 hours as needed. Do not exceed 6 doses (6 tablets or 30 mL) in 24 hours.

Usual Pediatric Dose for Cough:

6 years to 12 years:

2.5 mL of syrup (1.5 mg-5 mg/5 mL) or one-half tablet (1.5 mg-5 mg) orally every 4 to 6 hours as needed. Do not exceed 3 tablets or 15 mL in 24 hours.

> 12 years:

5 mL of syrup (1.5 mg-5 mg/5 mL) or I tablet (1.5 mg-5 mg) orally every 4 to 6 hours as needed. Do not exceed 6 doses (6 tablets or 30 mL) in 24 hours.

Narcotic (opioid) medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

• other narcotic medications--opioid pain medicine or prescription cough medicine;

• drugs that make you sleepy or slow your breathing--a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine; or

• drugs that affect serotonin levels in your body--medicine for depression, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting.

This list is not complete. Other drugs may interact with homatropine and hydrocodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.