Guaifenesin, Pseudoephedrine, and Dextromethorphan

• Dextromethorphan, Guaifenesin, and Pseudoephedrine
• Pseudoephedrine, Dextromethorphan, and Guaifenesin

Cough and upper respiratory tract symptoms: Oral: Note: Dosing may vary by product. Consult specific product labeling.

Liquid (dextromethorphan 15 mg/guaifenesin 175 mg/pseudoephedrine 30 mg per 5 mL): 10 mL every 8 hours, up to 30 mL per day.

Liquid (dextromethorphan 15 mg/guaifenesin 200 mg/pseudoephedrine 30 mg per 5 mL): 10 mL every 6 hours, up to 40 mL per day.

Liquid (dextromethorphan 20 mg per 5 mL) and tablets (guaifenesin 375 mg/pseudoephedrine 60 mg):

Liquid: 5 mL every 4 hours, up to 20 mL per day.

Tablets: One tablet every 4 to 6 hours, up to 4 tablets per day.

Tablets (dextromethorphan 15 mg/guaifenesin 190 mg/pseudoephedrine 30 mg): Two tablets every 6 hours, up to 8 tablets per day.

Tablets (dextromethorphan 15 mg/guaifenesin 400 mg/pseudoephedrine 60 mg): One tablet every 4 hours, up to 4 tablets per day.

Tablets (dextromethorphan 20 mg/guaifenesin 400 mg/pseudoephedrine 60 mg): One tablet every 4 to 6 hours, up to 4 tablets per day.

There are no dosage adjustments provided in the manufacturer's labeling.

Some products may contain phenylalanine.

See individual agents.

• Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)

• Patient may experience dizziness, anxiety, or insomnia (HCAHPS).

• Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.

Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for health care professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience, and judgment in diagnosing, treating, and advising patients.