Guaifenesin, hydrocodone, and phenylephrine

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Hydrocodone is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Guaifenesin, hydrocodone, and phenylephrine is a combination medicine used to treat cough, stuffy nose, and sinus congestion caused by allergies or the common cold.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Guaifenesin, hydrocodone, and phenylephrine may also be used for other purposes not listed in this medication guide.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This medicine may cause blurred vision or impair your thinking or reactions. Avoid driving or operating machinery until you know how guaifenesin, hydrocodone, and phenylephrine will affect you.

Avoid drinking alcohol while you are taking this medication.

Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains a decongestant or expectorant.