Etanercept-szzs
Name: Etanercept-szzs
Pharmacology
Mechanism of Action
Binds and inactivates TNF, thereby preventing synovial inflammation
Absorption
Bioavailability: 60%
Onset: 1-2 weeks
Peak plasma time (single 25-mg dose): 69 ± 34 hr
Peak plasma concentration (single 25-mg dose): 1.1 ± 0.6 mcg/mL
Distribution
Vd: 12 L
Elimination
Half-life: ~5 days
Clearance: 160 mL/hr (varies)