Etanercept-szzs

Name: Etanercept-szzs

Pharmacology

Mechanism of Action

Binds and inactivates TNF, thereby preventing synovial inflammation

Absorption

Bioavailability: 60%

Onset: 1-2 weeks

Peak plasma time (single 25-mg dose): 69 ± 34 hr

Peak plasma concentration (single 25-mg dose): 1.1 ± 0.6 mcg/mL

Distribution

Vd: 12 L

Elimination

Half-life: ~5 days

Clearance: 160 mL/hr (varies)

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