Diatrizoate Meglumine

• If you have an allergy to diatrizoate meglumine or any other part of diatrizoate meglumine.
• If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

• Cystografin
• Cystografin-Dilute

• Iodinated Contrast Media
• Radiological/Contrast Media, Ionic (High Osmolality)

Retrograde cystourethrography: Diagnostic agent for retrograde cystourethrography

Hypersensitivity to diatrizoate meglumine, salts of diatrizoic acid, or any component of the formulation

There are no dosage adjustments provided in the manufacturer’s labeling.

Diatrizoate meglumine 18% (Cystografin-Dilute): This is a ready-to-use product.

Diatrizoate meglumine 30%: Use undiluted or may dilute by adding sterile water or sterile saline to the bottle prior to instillation as follows:

100 mL bottle: Add 25 mL, 50 mL, or 67 mL (sterile water or sterile saline) for a total volume of 125 mL, 150 mL, or 167 mL, respectively.

300 mL bottle: Add 50 mL (sterile water or sterile saline) for a total volume of 350 mL.

Some products contain sodium.

Animal reproduction studies have not been conducted. In general, iodinated contrast media agents may cross the placenta; use should be avoided unless absolutely required to obtain diagnostic information that will influence the care of the mother or fetus during pregnancy (ACOG 2016; ACR 2015).