Dibucaine

You should not use dibucaine topical if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

• asthma or sulfite allergy.

It is not known whether dibucaine topical will harm an unborn baby. Ask a doctor before using this medicine if you are pregnant.

It is not known whether dibucaine topical passes into breast milk or if it could harm a nursing baby. Ask a doctor before using this medicine if you are breast-feeding a baby.

Do not give this medicine to a child younger than 12 years old without medical advice. Dibucaine topical should not be used on a child younger than 2 years old.

Do not apply this medicine near your eyes. Rinse with water if the medicine gets in your eyes.

Avoid exposure to sunlight or tanning beds. Dibucaine topical can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

• Blocks nerve conduction near application site and produces temporary loss of feeling or sensation.b

• Blocks the generation and conduction of nerve impulses by decreasing the rate of depolarization of the nerve membrane.b

• Importance of discontinuing therapy and consulting clinician if a rash or irritation develops during therapy.a c

• Importance of washing hands following administration.c

• Importance of avoiding contact with the eyes.a c

• Importance of using as directed and not applying in large quantities, particularly over raw surfaces or blistered areas.a

• Importance of discontinuing therapy and consulting clinician if dermatologic condition worsens or symptoms persist for >7 days or if redness, irritation, or bleeding occurs.a c

• Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed.c

• Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses.c

• Importance of informing patients of other important precautionary information. (See Cautions.)

Instill rectally each morning and evening and after each bowel movement using a rectal applicator. Additional ointment may be applied topically to anal tissues. No more than 30 grams should be used in a 24-hour period.

Hands should be washed before and after applying dibucaine topical.

Dibucaine topical should not be used extensively or for a prolonged time. If symptoms persist for more than 7 days, the product should be discontinued and a health care provider should be consulted.

Dibucaine topical should not be used on children less than 2 years of age or less than 35 pounds of body weight.

Safety and effectiveness have not been established in pediatric patients less than 12 years of age.

Data not available

Summary of Use during Lactation

Topical dibucaine has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. However, dibucaine ointment should not be applied to the nipple area. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Lidocaine

References

1. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

All products:

• Do not take dibucaine by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
• Clean affected part before use. Make sure to dry well.

Skin:

• Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
• Put a thin layer on the affected skin and rub in gently.
• It may be covered with a bandage or dressing.

Rectal:

• Wash your hands before and after use.
• Do not put this medicine into the rectum by using your fingers or any type of applicator. Follow what the doctor has told you to do.

What do I do if I miss a dose?

• If you use dibucaine on a regular basis, put on a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not put on 2 doses or extra doses.
• Many times this medicine is used on an as needed basis. Do not use more often than told by the doctor.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.