Desloratadine And Pseudoephedrine (Oral Route)

1. Clarinex-D

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of desloratadine and pseudoephedrine combination in the elderly with use in other age groups, elderly patients are more likely to be sensitive to the effects of this drug.

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Diabetes mellitus (sugar diabetes)—The decongestant in this medicine may put diabetic patients at a greater risk of having heart or blood vessel disease.

• Enlarged prostate or
• Urinary tract blockage or difficult urination—Some of the effects of antihistamines may make urinary problems worse.

• Glaucoma—A slight increase in inner eye pressure may occur.

• Heart or blood vessel disease or
• High blood pressure—The decongestant in this medicine may cause blood pressure to increase and may also speed up the heart rate.

• Kidney disease—Higher blood levels of desloratadine may result, which may increase the chance of side effects. If you are taking the 24 hour extended-release tablets, the dosage may need to be reduced. The 12 hour extended-release tablets should generally be avoided if you have kidney disease.

• Liver disease—Higher blood levels of desloratadine may result, which may increase the chance of side effects. This medicine should generally be avoided if you have liver disease.

• Overactive thyroid—If an overactive thyroid has caused a fast heart rate, desloratadine in this medicine may cause the heart rate to speed up further.

• Urinary retention—Condition may be worsened with use of pseudoephedrine

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (extended-release tablets [12 hour]):
  • For nasal congestion or rhinorrhea
    • Adults and teenagers—Oral, one tablet (2.5 milligrams desloratadine, 120 milligrams pseudoephedrine) two times a day 12 hours apart, taken with or without a meal
    • Children 4 years of age and older—Use and dose must be determined by your doctor.
    • Children and infants up to 4 years of age—Use is not recommended .

• For oral dosage form (extended-release tablets [24 hour]):
  • For nasal congestion or rhinorrhea
    • Adults and teenagers—Oral, one tablet (5 milligrams desloratadine, 240 milligrams pseudoephedrine) daily, taken with or without a meal
    • Children 4 years of age and older—Use and dose must be determined by your doctor.
    • Children and infants up to 4 years of age—Use is not recommended .