Daclizumab (Subcutaneous Route)

Daclizumab injection is used to treat the relapsing forms of multiple sclerosis (MS). This medicine will not cure MS, but it may slow some of the disabling effects and decrease the number of relapses of the disease.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Solution

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of daclizumab injection in the elderly.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Autoimmune hepatitis, history of or
• Liver disease—Should not be used in patients with these conditions.

• Depression, or history of or
• Eczema, history of or
• Mental health problems, or history of or
• Psoriasis, history of—Use with caution. May make these conditions worse.

• Infection, or history of—Daclizumab is not recommended for patients with an active infection, including tuberculosis. Caution should be used if you have a chronic infection or history of a recurring infection.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form:
  • For multiple sclerosis:
    • Adults—150 milligrams (mg) injected under your skin once a month.
    • Children—Use and dose must be determined by your doctor.

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Skip the missed dose if it is more than 2 weeks of your scheduled dose.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Keep the medicine in the original carton until you are ready to use it. You may also store it at room temperature for up to 30 days. Do not use external heat sources (eg, hot water) to warm the medicine. Do not put it back in the refrigerator after allowing it to warm to room temperature. Throw away after 30 days without refrigeration.

Do not reuse syringes and needles. Put used syringes and needles in a puncture-resistant disposable container, or dispose of them as directed by your doctor.