Deferasirox (Oral Route)

Name: Deferasirox (Oral Route)

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For chronic iron overload after blood transfusions:
    • For oral dosage form (tablets):
      • Adults and children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 14 milligrams (mg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 28 mg per kg per day.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
    • For oral dosage form (tablet for suspension):
      • Adults and children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 20 milligrams (mg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 40 mg per kg per day.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
  • For chronic iron overload in non-transfusion dependent thalassemia syndrome:
    • For oral dosage form (tablets):
      • Adults and children 10 years of age and older—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 7 milligrams (mg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 14 mg per kg per day.
      • Children younger than 10 years of age—Use and dose must be determined by your doctor.
    • For oral dosage form (tablet for suspension):
      • Adults and children 10 years of age and older—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 10 milligrams (mg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per kg per day.
      • Children younger than 10 years of age—Use and dose must be determined by your doctor.
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