Bimatoprost

Solution (eye drops): 0.01% and 0.03%

S Solutions should be store at 2 C to 25 C (36 F to 77 F).

Tell your doctor about all of the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• any other eye drops
• latanoprost (Xalatan)
• tafluprost (Zioptan)

This is not a complete list of bimatoprost drug interactions. Ask your doctor or pharmacist for more information.

• Store bimatoprost eye drops at room temperature or between 2° to 25°C (36° to 77°F).
• Keep this and all medicines out of the reach of children.

Ocular hypotensive agent; a synthetic prostaglandin analog.1

Storage

Ophthalmic

15–25°C in the original container.1

• Prostamide; a synthetic prostaglandin analog.1 2

• Mimics the effects of endogenous prostamides and exhibits little or no pharmacologic activity at prostanoid receptors.1 3 4 7

• Appears to reduce intraocular pressure (IOP) by facilitating outflow of aqueous humor through both the trabecular meshwork and uveoscleral routes.1 6 7

Store between 2°C to 25°C (36°F to 77°F).

Monitor IOP

One drop in the affected eye(s) once a day in the evening

Comments:
-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
-This drug should not be administered more than once a day since it has been shown that more frequent administration of prostaglandin analogs may decrease the intraocular pressure lowering effect.
-Reduction of the intraocular pressure starts approximately 4 hours after the first administration with maximum effect reached within approximately 8 to 12 hours.

Use: Reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension

One drop in the affected eye(s) once a day in the evening

Comments:
-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
-This drug should not be administered more than once a day since it has been shown that more frequent administration of prostaglandin analogs may decrease the intraocular pressure lowering effect.
-Reduction of the intraocular pressure starts approximately 4 hours after the first administration with maximum effect reached within approximately 8 to 12 hours.

Use: Reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension

Data not available

Administration advice:
-Do not touch dropper tip to any surface.

Storage requirements:
-Store below 25 C (77 F)
-To avoid contamination of the solution, keep container tightly closed.
-Discard contents 4 weeks after opening the bottle.

Patient advice:
-Patients should be instructed to wipe off any excess solution from the skin to reduce the risk of darkening of the eyelid skin.
-In order to minimize systemic absorption, patients should be instructed to apply pressure to the tear duct immediately following administration of the drug.