Bicillin L-A

Name: Bicillin L-A

Uses of Bicillin L-A

Penicillin G potassium is a prescription medication used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Side Effects of Bicillin L-A

Serious side effects have been reported with penicillin G potassium. See the “Drug Precautions” section.

Common side effects include:

  • an allergic reaction, with symptoms of itching, redness and warmth of skin, and swelling that may occur
  • itching of the skin
  • skin rash

This is not a complete list of penicillin G potassium side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

What is the most important information I should know about Bicillin L-A (penicillin G benzathine)?

You should not receive this medication if you are allergic to penicillin. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceftin, Cefzil, Omnicef, Keflex, and others.

Before you receive penicillin G benzathine, tell your doctor if you have asthma or a history of allergies, liver disease, kidney disease, or heart disease.

Be sure to receive all doses your doctor has prescribed. Your symptoms may get better before the infection is completely cleared.

After you have finished your treatment with penicillin G benzathine, your doctor may want to do tests to make sure your infection has completely cleared up.

How is Bicillin L-A (penicillin G benzathine)given?

Penicillin G benzathine is injected into a muscle. A healthcare provider will give you this injection.

Penicillin G benzathine must be injected slowly into a muscle of the buttock.

Penicillin G benzathine is sometimes given only once or only for a few days until your symptoms clear up. Be sure to receive all doses your doctor has prescribed. Your symptoms may get better before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics.

After you have finished your treatment with penicillin G benzathine, your doctor may want to do tests to make sure your infection has completely cleared up.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your penicillin G benzathine injection.

Precautions While Using Bicillin L-A

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Penicillins may cause diarrhea in some patients.

  • Check with your doctor if severe diarrhea occurs. Severe diarrhea may be a sign of a serious side effect. Do not take any diarrhea medicine without first checking with your doctor. Diarrhea medicines may make your diarrhea worse or make it last longer.
  • For mild diarrhea, diarrhea medicine containing kaolin or attapulgite (e.g., Kaopectate tablets, Diasorb) may be taken. However, other kinds of diarrhea medicine should not be taken. They may make your diarrhea worse or make it last longer.
  • If you have any questions about this or if mild diarrhea continues or gets worse, check with your health care professional.

Oral contraceptives (birth control pills) containing estrogen may not work properly if you take them while you are taking ampicillin, amoxicillin, or penicillin V. Unplanned pregnancies may occur. You should use a different or additional means of birth control while you are taking any of these penicillins. If you have any questions about this, check with your health care professional.

For diabetic patients:

  • Penicillins may cause false test results with some urine sugar tests. Check with your doctor before changing your diet or the dosage of your diabetes medicine.

Before you have any medical tests, tell the doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.

Bicillin L-A Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking this medicine and get emergency help immediately if any of the following effects occur:

Less common
  • Fast or irregular breathing
  • fever
  • joint pain
  • lightheadedness or fainting (sudden)
  • puffiness or swelling around the face
  • red, scaly skin
  • shortness of breath
  • skin rash, hives, itching

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Abdominal or stomach cramps and pain (severe)
  • abdominal tenderness
  • convulsions (seizures)
  • decreased amount of urine
  • diarrhea (watery and severe), which may also be bloody
  • mental depression
  • nausea and vomiting
  • pain at place of injection
  • sore throat and fever
  • unusual bleeding or bruising
  • yellow eyes or skin
Rare - For penicillin G procaine only
  • Agitation or combativeness
  • anxiety
  • confusion
  • fear of impending death
  • feeling, hearing, or seeing things that are not real

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea (mild)
  • headache
  • sore mouth or tongue
  • vaginal itching and discharge
  • white patches in the mouth and/or on the tongue

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Bicillin L-A?

  • If you need to store Bicillin L-A at home, talk with your doctor, nurse, or pharmacist about how to store it.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Bicillin L-A or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Bicillin L-A (penicillin G benzathine). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

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