Alkabel-SR

• If you have an allergy to hyoscyamine, atropine, scopolamine, phenobarbital, or any other part of Alkabel-SR (hyoscyamine, atropine, scopolamine, phenobarbital controlled-release tabs).
• If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• If you have any of these health problems: Bleeding problems, bowel block, glaucoma, a hernia that involves your stomach (hiatal hernia), myasthenia gravis, slow-moving GI (gastrointestinal) tract, trouble passing urine, or ulcerative colitis.
• If you have ever had porphyria.
• If you have been restless or overexcited in the past after taking phenobarbital.
• If you are addicted to drugs or alcohol, or have been in the past.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Alkabel-SR with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

• Store at room temperature.
• Store in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Check with your pharmacist about how to throw out unused drugs.

Regular release tablets: 1 to 2 tablets orally 3 to 4 times a day according to condition and severity of symptoms
Elixir: 5 to 10 mL orally 3 to 4 times a day according to condition and severity of symptoms
Extended release tablets: 1 tablet orally every 12 hours; if necessary, 1 tablet orally every 8 hours may be given

Elixir:
Initial dose:
4.5 kg to less than 9.1 kg: 0.5 mL orally every 4 hours or 0.75 mL orally every 6 hours
9.1 kg to less than 13.6 kg: 1 mL orally every 4 hours or 1.5 mL orally every 6 hours
13.6 kg to less than 22.7 kg: 1.5 mL orally every 4 hours or 2 mL orally every 6 hours
22.7 kg to less than 34 kg: 2.5 mL orally every 4 hours or 3.75 mL orally every 6 hours
34 kg to less than 45.4 kg: 3.75 mL orally every 4 hours or 1 mL orally every 6 hours
45.4 kg or greater: 5 mL orally every 4 hours or 7.5 mL orally every 6 hours

Elixir:
Initial dose:
4.5 kg to less than 9.1 kg: 0.5 mL orally every 4 hours or 0.75 mL orally every 6 hours
9.1 kg to less than 13.6 kg: 1 mL orally every 4 hours or 1.5 mL orally every 6 hours
13.6 kg to less than 22.7 kg: 1.5 mL orally every 4 hours or 2 mL orally every 6 hours
22.7 kg to less than 34 kg: 2.5 mL orally every 4 hours or 3.75 mL orally every 6 hours
34 kg to less than 45.4 kg: 3.75 mL orally every 4 hours or 1 mL orally every 6 hours
45.4 kg or greater: 5 mL orally every 4 hours or 7.5 mL orally every 6 hours

The phenobarbital component may be habit forming and should not be administered to individuals known to be addiction prone or to those with a history of physical and/or psychological dependence upon drugs.

Phenobarbital may decrease the effect of anticoagulants, and necessitate larger dosages of the anticoagulant for optimal effect. When phenobarbital is discontinued the dosage of anticoagulant may have to be decreased.

Because belladonna alkaloids are highly anticholinergic drugs, atropine/hyoscyamine/phenobarbital/scopolamine meets Beers criteria as a medication that is potentially inappropriate for use in older adults.

Data not available