Alka-Seltzer Morning Relief

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using aspirin and caffeine and call your doctor at once if you have:

• ringing in your ears, confusion, hallucinations, rapid breathing, seizure (convulsions);
• severe nausea, vomiting, or stomach pain;
• bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
• fever lasting longer than 3 days; or
• swelling, or pain lasting longer than 10 days.

Common side effects may include:

• upset stomach, heartburn;
• drowsiness; or
• mild headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take with food if aspirin and caffeine upsets your stomach.

Dissolve the powder or effervescent tablet in at least 4 ounces of water. Stir and drink this mixture right away.

If you need surgery, tell the surgeon ahead of time that you are using aspirin and caffeine. You may need to stop using the medicine for a short time.

Do not take this medication if you smell a strong vinegar odor in the aspirin and caffeine bottle. The medicine may no longer be effective.

Store at room temperature away from moisture and heat.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Aspirin 500 mg - caffeine 65 mg effervescent tablets:
2 tablets every 6 hours as needed. Maximum 4 tablets per 24 hours. Dissolve each tablet in 4 ounces of water before taking.

Aspirin 845 mg - caffeine 65 mg and aspirin 1000 mg - caffeine 65 mg:
1 powder on tongue every 6 hours as needed with a full glass of water or stir powder into a glass of water or other liquid
Maximum dose: 4 powders in 24 hours

Aspirin 500 mg - caffeine 32.5 mg:
Recommended dose: 2 caplets orally every 6 hours with a full glass of water
Maximum dose: 8 caplets in 24 hours

Detailed information concerning the pharmacokinetic disposition of aspirin and/or caffeine in patients with renal dysfunction or is not available. Aspirin should be used with caution in chronic renal insufficiency, since it may cause a transient decrease in renal function. The use of aspirin in patients with severe renal impairment (CrCl less than 10 mL/minute) is not recommended due to the potential for increased risk of salicylate toxicity.