Name: Acetylcholine

How is this medicine (Acetylcholine) best taken?

Use acetylcholine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into the eye.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about acetylcholine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about acetylcholine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using acetylcholine.

Review Date: October 4, 2017

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution Reconstituted, Intraocular, as chloride:

Miochol-E: 20 mg (1 ea) [contains mannitol]

Brand Names U.S.

  • Miochol-E

Onset of Action


Duration of Action

~20 minutes (Kanski 1968); duration as long as 6 hours has been reported (Roszkowska 1998)


Ophthalmic: Open under aseptic conditions only. Attach filter before irrigating eye. Instill into anterior chamber before or after securing one or more sutures; instillation should be gentle and parallel to the iris face and tangential to the pupil border; in cataract surgery, acetylcholine should be used only after delivery of the lens.

Forms of Medication

Acetylcholine is available in the following forms:

  • Injectable Solution


Mechanism of Action

Direct-acting parasympathomimetic neurotransmitter; causes contraction of sphincter muscles of the iris, which results in miosis and contraction of ciliary muscle and leads to accomodation spasm


Onset of action: Rapid

Duration: 6 hr

Administrative Information

LactMed Record Number


Last Revision Date



Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.