Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine is a combination medicine used to treat headache, fever, body aches, cough, chest congestion, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine may also be used for purposes not listed in this medication guide.

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Usual Adult Dose for Cough and Nasal Congestion:

Acetaminophen/dextromethorphan/guaifenesin/PSE 500 mg-20 mg-400 mg-60 mg oral tablet:
1 tablet orally every 4 to 6 hours not to exceed 4 tablets daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Acetaminophen/dextromethorphan/guaifenesin/PSE 500 mg-20 mg-400 mg-60 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 to 6 hours not to exceed 2 tablets daily.
12 years or older: 1 tablet orally every 4 to 6 hours not to exceed 4 tablets daily.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
• Not able to pass urine or change in how much urine is passed.
• A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

Acetaminophen/dextromethorphan/guaifenesin/PSE 500 mg-20 mg-400 mg-60 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 to 6 hours not to exceed 2 tablets daily.
12 years or older: 1 tablet orally every 4 to 6 hours not to exceed 4 tablets daily.

Data not available