Zonalon Topical

Name: Zonalon Topical

Zonalon Topical effects of
Zonalon Topical the effects of
Zonalon Topical side effects
Zonalon Topical drug
Zonalon Topical dosage
Zonalon Topical average dose
Zonalon Topical missed dose
Zonalon Topical serious side effects

Uses For Zonalon

Topical doxepin is used to relieve itching in patients with certain types of eczema. It appears to work by preventing the effects of histamine, which is a substance produced by the body that causes itching.

Doxepin is available only with your doctor's prescription.

Before Using Zonalon

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of doxepin in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of doxepin in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Amifampridine
Bepridil
Bromopride
Cisapride
Dronedarone
Grepafloxacin
Isocarboxazid
Levomethadyl
Linezolid
Mesoridazine
Methylene Blue
Metoclopramide
Moclobemide
Pimozide
Piperaquine
Ranolazine
Safinamide
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Tranylcypromine
Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acecainide
Aceclofenac
Acemetacin
Albuterol
Alfentanil
Almotriptan
Amiodarone
Amisulpride
Amitriptyline
Amoxapine
Amphetamine
Amtolmetin Guacil
Anagrelide
Aripiprazole
Aripiprazole Lauroxil
Arsenic Trioxide
Aspirin
Astemizole
Azimilide
Benzphetamine
Bretylium
Bromfenac
Bufexamac
Buprenorphine
Bupropion
Buserelin
Butorphanol
Celecoxib
Chloroquine
Choline Salicylate
Clarithromycin
Clonidine
Clonixin
Clorgyline
Clozapine
Codeine
Crizotinib
Cyclobenzaprine
Dabrafenib
Darunavir
Degarelix
Delamanid
Deslorelin
Desmopressin
Desvenlafaxine
Deutetrabenazine
Dexibuprofen
Dexketoprofen
Dextroamphetamine
Dextromethorphan
Diclofenac
Diflunisal
Dihydrocodeine
Dipyrone
Disopyramide
Dofetilide
Dolasetron
Domperidone
Donepezil
Droperidol
Droxicam
Efavirenz
Enflurane
Epinephrine
Erythromycin
Escitalopram
Eslicarbazepine Acetate
Etilefrine
Etodolac
Etofenamate
Etoricoxib
Felbinac
Fenoprofen
Fentanyl
Fepradinol
Feprazone
Floctafenine
Fluconazole
Flufenamic Acid
Fluoxetine
Flurbiprofen
Foscarnet
Frovatriptan
Gatifloxacin
Gemifloxacin
Gonadorelin
Goserelin
Granisetron
Halofantrine
Haloperidol
Halothane
Histrelin
Hydrocodone
Hydromorphone
Hydroxychloroquine
Hydroxytryptophan
Hydroxyzine
Ibuprofen
Ibutilide
Indomethacin
Iobenguane I 123
Iproniazid
Isoflurane
Isradipine
Ivabradine
Ketoconazole
Ketoprofen
Ketorolac
Leuprolide
Levalbuterol
Levofloxacin
Levomilnacipran
Levorphanol
Levothyroxine
Lisdexamfetamine
Lorcaserin
Lornoxicam
Loxoprofen
Lumiracoxib
Meclofenamate
Mefenamic Acid
Meloxicam
Meperidine
Methadone
Methamphetamine
Methoxamine
Metronidazole
Midodrine
Mirtazapine
Moricizine
Morniflumate
Morphine
Morphine Sulfate Liposome
Moxifloxacin
Nabumetone
Nafarelin
Nalbuphine
Naproxen
Naratriptan
Nebivolol
Nefopam
Nepafenac
Niflumic Acid
Nimesulide
Nimesulide Beta Cyclodextrin
Norepinephrine
Octreotide
Ondansetron
Oxaprozin
Oxilofrine
Oxycodone
Oxymetazoline
Oxymorphone
Oxyphenbutazone
Palonosetron
Panobinostat
Parecoxib
Pargyline
Paroxetine
Pasireotide
Pazopanib
Peginterferon Alfa-2b
Pentamidine
Pentazocine
Phenelzine
Phenylbutazone
Phenylephrine
Piketoprofen
Pimavanserin
Piroxicam
Pitolisant
Posaconazole
Pranoprofen
Procainamide
Procarbazine
Prochlorperazine
Proglumetacin
Propyphenazone
Proquazone
Quetiapine
Quinidine
Rasagiline
Remifentanil
Ribociclib
Risperidone
Rofecoxib
Salicylic Acid
Salsalate
Selegiline
Sematilide
Sertindole
Sertraline
Sevoflurane
Sodium Salicylate
Sotalol
Spiramycin
Sufentanil
Sulfamethoxazole
Sulindac
Sulpiride
Sultopride
Sumatriptan
Tacrolimus
Tapentadol
Tedisamil
Telithromycin
Tenoxicam
Tiaprofenic Acid
Tiotropium
Tolfenamic Acid
Tolmetin
Tramadol
Trazodone
Trifluoperazine
Trimethoprim
Triptorelin
Valdecoxib
Vandetanib
Vasopressin
Vemurafenib
Venlafaxine
Vilanterol
Vilazodone
Vinflunine
Vortioxetine
Zolmitriptan
Zotepine
Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acenocoumarol
Arbutamine
Bethanidine
Cannabis
Carbamazepine
Cimetidine
Dicumarol
Fosphenytoin
Guanethidine
Phenprocoumon
Phenytoin
Propoxyphene
Ramelteon
S-Adenosylmethionine
Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Proper Use of doxepin

This section provides information on the proper use of a number of products that contain doxepin. It may not be specific to Zonalon. Please read with care.

Topical doxepin is for external use only. Do not use this medicine orally, do not use it on the eyes, or inside of the vagina.

Use this medicine exactly as directed. Do not use more of it, do not use it more often, and do not use it for more than 8 days. Also, do not apply it to an area of skin larger than recommended by your doctor. To do so may increase the chance of side effects.

Apply a thin layer of doxepin cream to only the affected area(s) of the skin and rub in gently.

To help clear up your skin problem it is very important that you keep using topical doxepin for the full time of treatment. Do not miss any doses.

Do not cover with a bandage or otherwise wrap the area of skin being treated. This may increase the amount of medicine that gets into the bloodstream, thereby increasing the chance of side effects.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (cream):
- For itching due to eczema:
  - Adults—Apply a thin layer to the affected area(s) of the skin four times a day. Space the doses or applications at least three or four hours apart. Treatment may be continued for up to eight days.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Zonalon Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Burning, crawling, or tingling sensation of the skin
swelling at the site of application
worsening of eczema and itching

Rare

Fever

Symptoms of overdose

Abdominal pain and swelling
blurring of vision
convulsions (seizures)
decreased awareness or responsiveness
difficulty in breathing
difficulty in passing urine
dizziness, fainting, or lightheadedness
drowsiness
enlarged pupils
excessive dryness of mouth
extremely high fever or body temperature
extremely low body temperature
fast heartbeat
increased or excessive unconscious or jerking movements
incurable constipation
irregular heartbeat
unconsciousness
vomiting
weak pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning and/or stinging at the site of application
changes in taste
dizziness
drowsiness
dryness and tightness of skin
dryness of mouth and/or lips
emotional changes
headache
thirst
unusual tiredness or weakness

Less common

Anxiety
irritation, tingling, scaling, and cracking of skin
nausea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Side Effects

Burning/stinging at the application site, drowsiness, dizziness, dry mouth, blurred vision, or changes in taste may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: severe constipation, loss of coordination, ringing in the ears, persistent heartburn, mental/mood changes (e.g., agitation, confusion, depression), muscle weakness/spasms, numbness/tingling of the hands/feet, restlessness, decreased sexual ability/interest, trouble urinating, swelling of the hands/feet, weight gain.

Tell your doctor right away if any of these rare but very serious side effects occur: easy bruising/bleeding, persistent nausea/vomiting, signs of infection (e.g., fever, persistent sore throat), pain/redness/swelling of arms or legs, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.

Seek immediate medical attention if any of these rare but very serious side effects occur: slurred speech, fast/irregular heartbeat, vision changes, fainting, weakness on one side of the body, seizures.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

List Zonalon Cream side effects by likelihood and severity.