Voriconazole-oral

This medicine comes with a Patient Information Leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine.Take this medication by mouth, at least 1 hour before or 1 hour after meals, usually every 12 hours or as directed by your doctor.The dosage is based on your medical condition, response to therapy, and interacting drugs.This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.Continue to take this medication until the full prescribed amount is finished. Stopping the medication too early may result in a return of the infection.Inform your doctor if your condition persists or worsens.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: ergot alkaloids (such as ergotamine, dihydroergotamine), sirolimus, a certain combination HIV medication (such as efavirenz/emtricitabine/tenofovir).Many drugs besides voriconazole may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others.This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include certain alpha blockers (such as alfuzosin, silodosin, tamsulosin), birth control pills, cisapride, dronedarone, eletriptan, eplerenone, lurasidone, ranolazine, certain "statin" drugs (such as lovastatin, simvastatin), ticagrelor, tolvaptan, among others.Other medications can affect the removal of voriconazole from your body, which may affect how voriconazole works. Examples include certain barbiturates (such as mephobarbital, phenobarbital), carbamazepine, enzalutamide, primidone, rifamycins (such as rifabutin, rifampin), ritonavir, St. John's wort, among others.