Vitamin E
Name: Vitamin E
Cautions for Vitamin E
Contraindications
No known contraindications.a
Warnings/Precautions
Warnings
MortalityLong-term administration (>1 year) of high doses of vitamin E (≥400 units daily) may increase all-cause mortality.166 d
Specific Populations
PregnancyCategory A.c
LactationDistributed into human milk.c
Common Adverse Effects
Usually nontoxic at therapeutic doses.a
Interactions for Vitamin E
Specific Drugs
| Drug | Interaction | Comments |
|---|---|---|
| Anticoagulants, oral | Risk of hemorrhage with large doses of vitamin Ea | |
| Iron supplements | Vitamin E dosages ≥10 units/kg daily may delay response to iron therapy in children a | |
| Mineral oil | Possible impaired absorption of vitamin Ea | |
| Orlistat | Possible impaired absorption of fat-soluble vitamins, including vitamin E150 | Administer orlistat ≥2 hours before or after vitamin E150 152 156 158 |
| Vitamin A | Potential increase in absorption, utilization, and storage of vitamin Aa |