Typhim Vi

Name: Typhim Vi

What typhoid vaccines are available?

Typhoid vaccine can prevent typhoid. There are two vaccines to prevent typhoid. One is an inactivated (killed) vaccine given as a shot. The other is a live, attenuated (weakened) vaccine which is taken orally (by mouth).

Side Effects of Typhim Vi

Serious side effects have been reported with Typhim Vi. See Typhim Vi ”Precautions” section.

Common side effects of Typhim Vi include:

  • Fever 
  • Headache 
  • Redness or swelling at the site of the injection 

This is not a complete list of Typhim Vi side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about Typhim Vi side effects. You may report side effects to the FDA Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967 or http://www.fda.gov/vaers. 

Typhim Vi Precautions

Like any medicine, a vaccine could cause a serious problem, such as a severe allergic reaction. The risk of Typhim Vi causing serious harm, or death, is extremely small. Serious problems from Typhim Vi are very rare.      

Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. These would start a few minutes to a few hours after the vaccination.                                                                          

Do not receive Typhim Vi if you are allergic to Typhim Vi or to any of its ingredients. 

Typhim Vi Dosage

Receive this vaccination exactly as prescribed by your healthcare provider.

The recommended dose of Typhim Vi for persons two years and over is a single dose of (0.5mL). 

Typhim Vi is administered by a healthcare provider:

  • in the muscle of the arm (deltoid) in adults 
  • in the muscle of the arm (deltoid) or in the muscle of the thigh (muscle is on the outside of the leg in the mid- to upper-thigh) for children

What is typhoid vaccine?

Typhoid (also called "typhoid fever") is a serious disease caused by Salmonella typhi bacteria. Typhoid can be fatal if left untreated.

Typhoid can cause high fever, muscle aches, severe headache, weakness, confusion or agitation, loss of appetite, stomach pain, diarrhea or constipation, and rose-colored spots on the skin.

Untreated typhoid infection may lead to kidney failure, or intestinal bleeding caused by perforation (forming of a hole), which can be fatal. If the infection spreads to the gallbladder, the infected person may become a chronic carrier of the bacteria that causes typhoid. A carrier may have no symptoms but is capable of spreading the infection to others.

Typhoid is spread through contact with the stool (bowel movements) of a person infected with the bacteria. This usually occurs by eating food or drinking water that has become contaminated with feces from an infected person. Once in the digestive tract, typhoid infection can spread to the blood and other parts of the body.

Typhoid fever is most common in non-industrialized parts of the world, especially Asia, Africa, and Central or South America. People who travel to those regions are at risk of coming into contact with the disease.

The typhoid vaccine is used to help prevent this disease in adults and children who are at least 2 years old. Although not part of a routine immunization schedule in the U.S., typhoid vaccine is recommended for people who travel to areas where the disease is common.

This vaccine works by exposing you to a small amount of the bacteria, which causes your body to develop immunity to the disease.

Typhoid vaccine will not treat an active infection that has already developed in the body, and will not prevent any disease caused by bacteria other than Salmonella typhi.

Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.

Uses For Typhim Vi

Typhoid fever is a serious disease that can cause death. It is caused by a germ called Salmonella typhi, and is spread most often through infected food or water. Typhoid may also be spread by close person-to-person contact with infected persons (such as occurs with persons living in the same household). Some infected persons do not appear to be sick, but they can still spread the germ to others.

Typhoid fever is very rare in the U.S. and other areas of the world that have good water and sewage (waste) systems. However, it is a problem in parts of the world that do not have such systems. If you are traveling to certain countries or remote, out-of-the-way areas, typhoid vaccine will help protect you from typhoid fever. The U.S. Centers for Disease Control (CDC) currently recommend caution in the following areas of the world:

  • Africa
  • Asia
  • Latin America

Typhoid vaccine given by injection helps prevent typhoid fever, but does not provide 100% protection. Therefore, it is very important to avoid infected persons and food and water that may be infected, even if you have received the vaccine.

To get the best possible protection against typhoid, you should receive the vaccine at least 1 week before you travel to areas where you may be exposed to typhoid.

If you will be traveling regularly to parts of the world where typhoid is a problem, you should get a booster (repeat) dose of the vaccine every 2 years.

Typhoid vaccine is to be used only by or under the supervision of a doctor.

Uses of Typhim Vi

  • It is used to prevent typhoid disease.

What are some things I need to know or do while I take Typhim Vi?

  • Tell all of your health care providers that you take Typhim Vi. This includes your doctors, nurses, pharmacists, and dentists.
  • This medicine may not protect all people who use it. Talk with the doctor.
  • Use care when eating food and drinking water in disease-affected areas. If you have questions, talk with your doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Usual Pediatric Dose for Typhoid Prophylaxis

2 years and older:
0.5 mL, IM, once

-Reimmunization is recommended every 2 years, with a single dose, for travelers with repeated or continued exposure to S. typhi.

Renal Dose Adjustments

Data not available