Ticagrelor Tablets for Oral Administration

Dosage Forms And Strengths

BRILINTA (ticagrelor) 90 mg is supplied as a round, biconvex, yellow, film-coated tablet marked with a “90” above “T” on one side.

BRILINTA (ticagrelor) 60 mg is supplied as a round, biconvex, pink, film-coated tablet marked with “60” above “T” on one side.

Storage And Handling

BRILINTA (ticagrelor) 90 mg is supplied as a round, biconvex, yellow, film-coated tablet with a “90” above “T” on one side:

Bottles of 14 – NDC 0186-0777-28
Bottles of 60 – NDC 0186-0777-60
100 count Hospital Unit Dose – NDC 0186-0777-39

BRILINTA (ticagrelor) 60 mg is supplied as a round, biconvex, pink, film-coated tablet with a “60” above “T” on one side:

Bottles of 60 – NDC 0186-0776-60

Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP controlled room temperature].

Distributed by: AstraZeneca Pharmaceuticals LP, Wilmington, DE 19850. Revised: Sep 2016

Ticagrelor keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions.

Ticagrelor is used to lower your risk of having a stroke or serious heart problems after you have had a heart attack or severe chest pain (angina).

Ticagrelor may also be used for purposes not listed in this medication guide.

You should not use this medication if you are allergic to ticagrelor, or if you have:

• severe liver disease;
• any active bleeding;
• stomach ulcer or bleeding; or
• a history of bleeding in the brain (such as from a head injury).

To make sure you can safely take ticagrelor, tell your doctor if you have any of these other conditions:

• liver disease;
• asthma, COPD (chronic obstructive pulmonary disorder) or other breathing problem;
• a history of stomach ulcer or colon polyps;
• a history of stroke; or
• a history of bleeding or blood clotting disorder.

Ticagrelor may cause you to bleed more easily, especially if you have:

• a recent surgery or bleeding injury;
• a disease affecting the blood vessels in your brain;
• a history of stroke;
• a history of bleeding problems;
• a history of stomach or intestinal bleeding; or
• if you are 65 or older.

FDA pregnancy category C. It is not known whether ticagrelor will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether ticagrelor passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using ticagrelor.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.