Sumatriptan Nasal Powder

• It is used to treat migraine headaches.
• It is used to treat cluster headaches.

• If you have an allergy to sumatriptan succinate or any other part of sumatriptan nasal powder.
• If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• If you have any of these health problems: High blood pressure or some types of migraine headaches like hemiplegic or basilar migraine.
• If you have ever had any of these health problems: Chest pain or pressure; diseased arteries going to the legs or arms; heart attack; heart disease; poor blood flow in the heart, brain, bowel, or kidney; stroke; or a heartbeat that is not normal like Wolff-Parkinson-White syndrome.
• If you have liver disease.
• If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking this medicine within 14 days of those drugs can cause very bad high blood pressure.
• If you are taking another drug that has the same drug in it.
• If you have taken almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, or zolmitriptan in the last 24 hours.
• If you have taken ergotamine, methysergide, dihydroergotamine, or any drug like them in the last 24 hours.
• If you are breast-feeding or plan to breast-feed.

This is not a list of all drugs or health problems that interact with sumatriptan nasal powder.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Follow how to use as you have been told by the doctor or read the package insert.
• For the nose only.
• Use sumatriptan nasal powder as early as you can after the attack has started.
• Use nosepiece right after taking it out of the foil pouch.
• Only use the device that comes with this medicine. Do not use any other devices.
• If your headache comes back after the first dose, 1 more dose may be taken 2 hours after the first one.

What do I do if I miss a dose?

• This medicine is taken on an as needed basis. Do not take more often than told by the doctor.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Seizures.
• Loss of eyesight. This can be long-lasting.
• Very bad headache or if headache is not better after the first dose.
• A burning, numbness, or tingling feeling that is not normal.
• Change in color of skin to a bluish color like on the lips, nail beds, fingers, or toes.
• Hard stools (constipation).
• Loose stools (diarrhea).
• Very upset stomach or throwing up.
• Very bad belly pain or bloody loose stools.
• Fever.
• Weight loss.
• Leg cramps.
• Feeling of heaviness or tightness in the leg muscles.
• Feeling cold.
• Burning or aching pain in the feet or toes.
• Change in hearing.
• A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if you take sumatriptan nasal powder with drugs for depression, migraines, or certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; very bad diarrhea, upset stomach, or throwing up; or very bad headache.

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Dizziness.
• Flushing.
• Feeling of warmth.
• Feeling tired or weak.
• Feeling sleepy.
• Upset stomach or throwing up.
• Bad taste in your mouth.
• Nose and throat irritation.
• Runny nose.
• Stuffy nose.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on: 

• your age
• the condition being treated
• how severe your condition is
• other medical conditions you have
• how you react to the first dose

What are you taking this medication for?

Brand: Onzetra Xsail

• Typical starting dosage: 22 mg taken when migraine symptoms appear. You’ll take the 22 mg dose using one 11 mg nosepiece in each nostril.
• Dosage increases: If you don’t get enough relief within 2 hours of the first dose, talk to your doctor. They may suggest that you take another dose.
• Maximum dosage: Do not take more than 44 mg (4 nosepieces) within a 24-hour period.

It has not been confirmed that sumatriptan is safe and effective for use in children. Do not use in people younger than 18 years.

The kidneys, liver, and heart of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lowered dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body. Before prescribing sumatriptan, your doctor should also evaluate the condition of your heart if you have certain risks for heart disease.

Take this drug at the time(s) recommended by your doctor

Store this drug carefully

A prescription for this medication is refillable

Travel

Self-management

Clinical monitoring

Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead

Hidden costs

Insurance

Are there any alternatives?