Sporanox PulsePak

Itraconazole is an antifungal medication that fights infections caused by fungus.

Itraconazole is used to treat infections caused by fungus, which can invade any part of the body including the lungs, mouth or throat, toenails, or fingernails.

Itraconazole may also be used for purposes not listed in this medication guide.

You should not take this medicine if you have ever had congestive heart failure.

Many drugs can interact with itraconazole, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with itraconazole.

Life-threatening side effects may occur if you take itraconazole with cisapride, dihydroergotamine, disopyramide, dofetilide, dronedarone, eplerenone, ergonovine, ergotamine, felodipine, irinotecan, ivabradine, lurasidone, lovastatin, methadone, methylergonovine, oral midazolam, nisoldipine, pimozide, quinidine, ranolazine, simvastatin, ticagrelor, or triazolam.

If you have liver or kidney disease, you should not take itraconazole with colchicine, fesoterodine, solifenacin, or telithromycin.

You should not take itraconazole to treat a toenail or fingernail infection if you are pregnant or may become pregnant during treatment.

You should not take this medicine if you are allergic to itraconazole or similar medicines such as fluconazole or ketoconazole, or if you have ever had congestive heart failure.

You should not take itraconazole to treat a toenail or fingernail infection if you are pregnant or may become pregnant during treatment.

Life-threatening side effects may occur if you take itraconazole with:

• cisapride;

• irinotecan;

• methadone;

• ranolazine;

• ticagrelor;

• lurasidone or pimozide (anti-psychotic medications);

• lovastatin or simvastatin (cholesterol-lowering medicines);

• dihydroergotamine, ergonovine, ergotamine, or methylergonovine (ergot medicines);

• eplerenone, felodipine, ivabradine, or nisoldipine (heart or blood pressure medicines);

• disopyramide, dofetilide, dronedarone, or quinidine (medicines for heart rhythm disorders); or

• oral midazolam, or triazolam (Valium-like sedatives).

If you have liver or kidney disease, you should not take itraconazole with colchicine, fesoterodine, solifenacin, or telithromycin.

To make sure itraconazole is safe for you, tell your doctor if you have:

• heart disease, a heart rhythm disorder, circulation problems, or a history of stroke;

• chronic obstructive pulmonary disease (COPD) or other breathing disorder;

• kidney disease;

• cirrhosis or other liver disease;

• cystic fibrosis; or

• a personal or family history of long QT syndrome.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 months after your last dose.

Itraconazole can pass into breast milk and may affect the nursing baby. Tell your doctor if you are breast-feeding.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid taking antacids within 1 hour before or 2 hours after you take itraconazole. Some antacids can make it harder for your body to absorb itraconazole.

Many drugs can interact with itraconazole, and some drugs should not be used together. Tell your doctor about all your current medicines and any you start or stop using, especially:

• an antibiotic;

• antipsychotic medicine or a sedative;

• an antiviral medicine to treat hepatitis C or HIV/AIDS;

• medicine to prevent blood clots;

• cancer medicine;

• drugs to treat urinary problems;

• heart or blood pressure medication;

• immunosuppressants, or medicine to prevent organ transplant rejection;

• medicine to treat high cholesterol;

• migraine headache medication;

• narcotic (opioid) pain medicine;

• seizure medicine; or

• steroid medication.

This list is not complete and many other drugs can interact with itraconazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Give a list of all your medicines to any healthcare provider who treats you.