Sotalol-oral

Name: Sotalol-oral

Drug interactions

  • Combining sotalol with beta-blockers such as atenolol (Tenormin), propranolol (Inderal), metoprolol (Lopressor), or calcium channel blockers such as verapamil (Calan, Isoptin, Verelan, Covera-HS) or diltiazem (Cardizem, Dilacor, Tiazac), may excessively slow heart rate or cause a block in the conduction of electrical impulses through the heart. Additionally, these combinations may further reduce blood pressure, possibly leading to hypotension.
  • Digoxin and beta-blockers slow conduction of impulses in the heart and decrease heart rate. Combining them can increase the risk of slow heart rate.
  • Sotalol may cause high blood glucose, and the dosage of insulin or antidiabetic drugs may require adjustment. It also may mask symptoms of low blood glucose (hypoglycemia).
  • Administration of sotalol within 2 hours of antacids containing aluminum oxide and magnesium hydroxide may reduce blood concentrations of sotalol by 26%. This reduces the effect of sotalol. This combination should be avoided or the antacid should be taken two hours after the sotalol.

Storage

Store at room temperature, 15 C - 30 C (59 F - 86 F).

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