Sodium Iodide

Sodium iodide is an iodide salt that is formed into an injectable medicine.

Sodium iodide is used to treat or prevent iodine deficiency caused by poor nutrition or poor absorption by the body.

Sodium iodide may also be used to treat a thyroid disorder.

Sodium iodide may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

You should not use this medication if you are allergic to sodium iodide.

To make sure sodium iodide is safe for you, tell your doctor if you have:

• kidney disease; or
• if you use iodine and povidone antiseptic solution (Betadine) on your skin.

Air levels of iodine are higher near an ocean, and iodine can be absorbed through your lungs. Tell your doctor where you live and where you have recently traveled or plan to travel to during treatment.

Your doctor will determine whether or not this medication is safe or if it will harm the unborn baby. Before you use sodium iodide, tell your doctor if you are pregnant or planning to become pregnant during treatment.

Sodium iodide can pass into breast milk. Tell your doctor if you are breast-feeding a baby.

You should not use this medication if you are allergic to sodium iodide.

To make sure sodium iodide is safe for you, tell your doctor if you have:

• kidney disease; or

• if you use iodine and povidone antiseptic solution (Betadine) on your skin.

Air levels of iodine are higher near an ocean, and iodine can be absorbed through your lungs. Tell your doctor where you live and where you have recently traveled or plan to travel to during treatment.

Your doctor will determine whether or not this medication is safe or if it will harm the unborn baby. Before you use sodium iodide, tell your doctor if you are pregnant or planning to become pregnant during treatment.

Sodium iodide can pass into breast milk. Tell your doctor if you are breast-feeding a baby.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Injectable sodium iodide is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Sodium iodide injection must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.

Use a disposable needle only once, then throw away in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

If you need medical tests, tell the doctor ahead of time that you are using sodium iodide.

Sodium iodide may be only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must eat to help control your condition.

Store sodium iodide at room temperature away from moisture and heat.

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

• Iodopen

Iodine supplement: Supplement to intravenous solutions given for total parenteral nutrition (TPN) to prevent depletion of endogenous iodine stores and subsequent deficiency symptoms.

Refer to adult dosing.

Iodine supplement: Children and Adolescents: IV: 2 to 3 mcg/kg/day administered in TPN solution

Dietary reference intake for iodine (IOM, 2001):

Infants 0 to 6 months: Adequate intake: 110 mcg/day

Infants 7 to 12 months: Adequate intake: 130 mcg/day

Children 1 to 8 years: RDA: 90 mcg/day

Children 9 to 13 years: RDA: 120 mcg/day

Adolescents ≥14 years: RDA: 150 mcg/day

Pregnancy: RDA: 220 mcg/day

Breast-feeding: RDA: 290 mcg/day

There are no dosage adjustments provided in the manufacturer's labeling; however, dosage may need to be adjusted, reduced, or omitted.

Sodium iodide for injection may be used in pregnant women as an iodine supplement when needed in total parenteral nutrition (TPN). An adequate amount of iodine intake is essential for thyroid function. Iodine crosses the placenta and requirements are increased during pregnancy. Iodine deficiency in pregnancy can lead to neurologic damage in the newborn; an extreme form, cretinism, is characterized by gross mental retardation, short stature, deaf mutism, and spasticity. Large amounts of iodine during pregnancy can cause fetal goiter or hyperthyroidism (IOM 2001).