Omnipaque 140

Name: Omnipaque 140

Before Using Omnipaque 140

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of iohexol in children. Some pediatric patients with certain medical conditions may have more unwanted side effects which may require caution in patients receiving iohexol.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of iohexol in the elderly. However, elderly patients are more likely to have unwanted side effects which may require caution in patients receiving iohexol.

Pregnancy

Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Metformin

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amiodarone

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse or
  • Heart or blood vessel disease or
  • Multiple sclerosis or
  • Seizures or epilepsy, history of—Iohexol injection should be used with caution in these patients.
  • Allergies or hypersensitivities, or
  • Allergic rhinitis (hay fever) or
  • Allergy to a contrast agent, history of or
  • Allergy to food or
  • Allergy to iodine or
  • Asthma—Use with caution. May increase risk of having allergic reactions.
  • Anuria (not able to pass urine) or
  • Blood vessel disease, severe or
  • Congestive heart failure or
  • Dehydration or
  • Diabetes or
  • Diabetic nephropathy or
  • Kidney disease or
  • Multiple myeloma (cancer of plasma cells) or
  • Paraproteinemia (high amount of paraprotein in the blood)—May increase risk of having kidney failure.
  • Blood clotting problems (eg, thrombosis) or
  • Heart or blood vessel disease (eg, arteriosclerosis) or
  • Hypertension (high blood pressure) or
  • Hyperthyroidism (overactive thyroid) or
  • Kidney disease, severe or
  • Liver disease or
  • Pheochromocytoma (adrenal problem) or
  • Sickle cell anemia (inherited blood disorder)—Use with caution. May make these conditions worse.
  • Homocystinuria (genetic disease)—Patients with this condition should avoid undergoing angiography because of the increased risk of having blood clotting problems.
  • Infection—Iohexol injection should not be given for myelography in patients with this condition.

For the Consumer

Applies to iohexol: solution

Along with its needed effects, iohexol (the active ingredient contained in Omnipaque 140) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking iohexol:

More commonOral or rectal route
  • Swelling or pain
Less commonIntravascular route
  • Arm, back, or jaw pain
  • chest pain or discomfort
  • chest tightness or heaviness
  • difficulty breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • nausea
  • shortness of breath
  • sweating
  • swelling in the throat
Less commonOral or rectal route
  • Blurred vision
  • confusion
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • headache
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • sweating
  • unusual tiredness or weakness
RareIntrathecal route
  • Blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • confusion
  • dizziness or lightheadedness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • feeling of constant movement of self or surroundings
  • headache
  • nervousness
  • pounding in the ears
  • seizures
  • slow or fast heartbeat
  • sweating
  • unusual tiredness or weakness
RareIntravascular route
  • Blurred vision
  • confusion
  • dilated neck veins
  • dizziness or lightheadedness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • extreme fatigue
  • fast, pounding, or irregular heartbeat or pulse
  • feeling cold
  • feeling of constant movement of self or surroundings
  • fever
  • irregular breathing
  • pale skin
  • seizures
  • sensation of spinning
  • swelling of the face, fingers, feet, or lower legs
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • weight gain
RareOral or rectal route
  • Muscle weakness

Some side effects of iohexol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More commonIntrathecal route
  • Nausea
  • pain in the neck, back, or nerve
More commonOral or rectal route
  • Abdominal or stomach pain
  • bloated or full feeling
  • diarrhea
  • excess air or gas in the stomach or intestines
  • nausea
  • passing gas
  • vomiting
Less commonIntrathecal route
  • Vomiting
Less commonIntravascular route
  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • headache
Less commonOral or rectal route
  • Hives or welts, itching, or skin rash
  • redness of the skin
  • sleepiness or unusual drowsiness
RareIntrathecal route
  • Change in color vision
  • continuing ringing or buzzing or other unexplained noise in the ears
  • difficulty seeing at night
  • drowsiness
  • hearing loss
  • increased sensitivity of the eyes to sunlight
  • loss of appetite
  • sensation of spinning
RareIntravascular route
  • Acid or sour stomach
  • anxiety
  • belching
  • chills
  • cold sweats
  • coma
  • cool, pale skin
  • cough
  • depression
  • diarrhea
  • dry mouth
  • heartburn
  • hives or welts, itching, or rash
  • increased hunger
  • indigestion
  • nightmares
  • redness of the skin
  • runny nose
  • shakiness
  • sleepiness or unusual drowsiness
  • slurred speech
  • sneezing
  • stomach discomfort, upset, or pain
  • stuffy nose
  • uncontrolled eye movements
  • vomiting

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